217434-85-0

Upstream product

• 63383-26-6 1-chloro-4-(vinylsulfinyl)benzene 
• 1262638-55-0 1-chloro-4-(2-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyloxy)ethylsulfinyl)benzene 
• 16411-16-8 p-chlorophenyl vinyl sulfide 

Downstream Products

• 1262638-60-7 (1S,2S,4S)-2-(4-chlorophenylsulfinyl)-7-oxabicyclo[2.2.1]hept-5-ene 
• 1262638-75-4 (1S,2R,4S)-2-(4-chlorophenylsulfinyl)-7-oxabicyclo[2.2.1]hept-5-ene 
• 1262638-62-9 (1S,2S,4S)-2-(4-chlorophenylsulfinyl)-1-methyl-7-oxabicyclo[2.2.1]hept-5-ene 
• 1262638-77-6 (1S,2S,4S)-2-(4-chlorophenylsulfinyl)-1,4-dimethyl-7-oxabicyclo[2.2.1]hept-5-ene 
• 1262638-63-0 (1S,2S,4S)-2-(4-chlorophenylsulfonyl)-1-methyl-7-oxabicyclo[2.2.1]hept-5-ene 
• 1262638-64-1 (1S,2S,4S)-2-(4-chlorophenylsulfonyl)-1,4-dimethyl-7-oxabicyclo[2.2.1]hept-5-ene 

Relevant academic research and scientific papers

Enantioselective synthesis of 2,2,5-triand 2,2,5,5-tetrasubstituted tetrahydrofurans via [4 + 2] cycloaddition and ring-opening cross-metathesis

A chiral vinyl sulfoxide has been developed that undergoes highly diastereoselective Diels-Alder cycloadditions with various substituted furans in excellent yield. The cycloadducts can be stereoselectively transformed into 2,2,5-tri-and 2,2,5,5-tetrasubstituted tetrahydrofurans, which are structural subunits of many natural products, via regioselective ring-opening metathesis/cross-metathesis or oxidative cleavage/refunctionalization.