217448-49-2 Usage
Properties and Specific Content of 1H-Indole, 2-iodo-1-[(4-methoxyphenyl)sulfonyl]-
A chemical compound consisting of 15 carbon atoms, 13 hydrogen atoms, 1 iodine atom, 1 nitrogen atom, 4 oxygen atoms, and 1 sulfur atom.
Indole core structure
A bicyclic aromatic structure with a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring.
Iodine atom attached
The presence of an iodine atom in the compound can increase its polarity and lipophilicity, which may affect its pharmacokinetic and pharmacodynamic properties.
Sulfonyl group (-SO2-)
A functional group consisting of a sulfur atom double-bonded to two oxygen atoms, which can participate in various chemical reactions and contribute to the compound's biological activity.
4-Methoxyphenyl group
A phenyl ring (a six-membered aromatic ring) with a methoxy group (-OCH3) attached to the fourth position, which can influence the compound's pharmacological properties and solubility.
Potential applications in organic and medicinal chemistry
The presence of the iodine and sulfonyl groups allows the compound to participate in various chemical reactions, such as nucleophilic substitution, electrophilic aromatic substitution, and oxidation reactions.
Versatile chemical compound
The combination of different functional groups in the molecule makes it a promising candidate for the development of new drugs or other related products.
Development of new drugs or related products
The compound's unique structure and functional groups may lead to the discovery of new therapeutic agents or other applications in the fields of organic and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 217448-49-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,7,4,4 and 8 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 217448-49:
(8*2)+(7*1)+(6*7)+(5*4)+(4*4)+(3*8)+(2*4)+(1*9)=142
142 % 10 = 2
So 217448-49-2 is a valid CAS Registry Number.
217448-49-2Relevant academic research and scientific papers
Application of the Pd-catalyzed heteroarylation to the synthesis of 5- (indol-2'-yl)pyridin-2-one and 5-(indol-2'-yl)pyran-2-one
Danieli, Bruno,Lesma, Giordano,Martinelli, Marisa,Passarella, Daniele,Peretto, Ilaria,Silvani, Alessandra
, p. 14081 - 14088 (2007/10/03)
The synthesis of 5-(indol-2'-yl)pyridin-2-ones and 5-(indol-2'-yl)pyran- 2-one by Pd-catalyzed reactions is described. The best results are obtained using 2-indolylstannanes or 2-indolylzinc halides to be coupled with 5- bromopyridin-2-ones or 5-bromopyran-2-one in the presence of Pd(PPh3)4 as catalyst. Other Pd-catalyzed reactions are discussed.
