217454-98-3Relevant academic research and scientific papers
Synthesis and biological evaluation of 4-chloro-3,5- dinitrobenzotrifluoride analogues as antileishmanial agents
Pitzer, Kevin K.,Werbovetz, Karl A.,Brendle, James J.,Scovill, John P.
, p. 4885 - 4889 (1998)
Desnitro analogues of 4-chloro-3,5-dinitrobenzotrifluoride (chloralin) (2), an in vitro microtubule inhibitor of several Leishmania species, have been synthesized from 2-halo-5-(trifluoromethyl)benzenesulfonyl chlorides 4 and 5. The analogues exhibited mo
Cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compostions containing them
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Page/Page column 5, (2010/02/17)
Compounds of formula (I): wherein: RCy represents an unsubstituted or substituted cycloalkyl group or cycloalkylalkyl group,R1, R2, R3 and R4, which may be the same or different, each represent a hydrogen or halogen atom or a nitro group; a cyano group; a hydroxy group; an alkoxy group; an alkyl group; an unsubstituted or substituted amino group; a carboxy group; an alkoxycarbonyl group; an aryloxycarbonyl group; an unsubstituted or substituted aminocarbonyl group. Medicinal products containing the same which are useful in treating or preventing conditions treatable by an AMPA receptor modulator.
