217455-89-5

Upstream product

• 2049-94-7 (3-methylbutyl)benzene 
• 590-86-3 isovaleraldehyde 
• 1565-86-2 3-Methyl-1-phenyl-1-butanol 

Downstream Products

• 1039935-79-9 (+/-)-3-Methyl-1-phenyl-butanthiol-⁽¹⁾ 
• 1325730-31-1 (S)-4,4,5,5-tetramethyl-2-(3-methyl-1-phenylbutyl)-1,3,2-dioxaborolane 
• 1338246-58-4 (R)-4,4,5,5-tetramethyl-2-(3-methyl-1-phenylbutyl)-1,3,2-dioxaborolane 
• 66283-21-4 (S)-3-methyl-1-phenylbutanol 
• 1565-86-2 (R)-3-methyl-1-phenylbutanol 

Relevant academic research and scientific papers

Cu-Catalyzed Site-Selective Benzylic Chlorination Enabling Net C–H Coupling with Oxidatively Sensitive Nucleophiles

Site-selective chlorination of benzylic C–H bonds is achieved using a CuICl/bis(oxazoline) catalyst with N-fluorobenzenesulfonimide as the oxidant and KCl as a chloride source. This method exhibits higher benzylic selectivity, relative to estab

Copper(I)-Catalyzed Enantioconvergent Borylation of Racemic Benzyl Chlorides Enabled by Quadrant-by-Quadrant Structure Modification of Chiral Bisphosphine Ligands

The first copper(I)-catalyzed enantioselective borylation of racemic benzyl chlorides has been realized by a quadrant-by-quadrant structure modulation of QuinoxP*-type bisphosphine ligands. This reaction converts racemic mixtures of secondary benzyl chlorides into the corresponding chiral benzylboronates with high enantioselectivity (up to 92 % ee). The results of mechanistic studies suggest the formation of a benzylic radical intermediate. The results of DFT calculations indicate that the optimal bisphosphine-copper(I) catalyst engages in noncovalent interactions that efficiently recognize the radical intermediate, and leads to high levels of enantioselectivity.

Interpretation of retention indices in gas chromatography for establishing structures of isomeric products of alkylarenes radical chlorination

By an example of previously uncharacterized products obtained by alkylarenes radical chlorination was demonstrated that combination of various interpretation methods applied to the retention indices (RI) in the gas chromatography on the standard nonpolar phases (comparison of RI of products and initial compounds, characteristics of succession of the chromatographic elution of the structural isomers with the use of estimation of molecular dynamic parameters, application of the additive schemes to RI calculation, and using of structural analogy CH3?Cl for testing the results obtained) permitted unambiguous identification of the structure even without data of mass spectrometry.