21746-93-0

Basic information

• Product Name: 2-(2-phenoxyethyl)oxirane
• Synonyms: 2-(2-phenoxyethyl)oxirane
• CAS NO: 21746-93-0
• Molecular Weight: 164.204
• Mol File: 21746-93-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-phenoxyethyl)oxirane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-phenoxyethyl)oxirane(21746-93-0)
• EPA Substance Registry System: 2-(2-phenoxyethyl)oxirane(21746-93-0)

Safety Data

• Hazardous Substances Data: 21746-93-0(Hazardous Substances Data)

Upstream product

• 1200-03-9 4-bromophenyl butyl ether 
• 2653-89-6 4-phenoxy-1-butene 

Downstream Products

• 1352331-62-4 6-(5-methoxy-2-methylphenyl)-1-phenoxy-3-hexanol 
• 127331-76-4 α-(2-phenoxyethyl)-4-phenyl-1-piperazineethanol 

Relevant articles and documents

Synthesis of (-)-astrogorgiadiol

Astrogorgiadiol is a naturally occurring Vitamin D analogue that, in cell culture, downregulates the production of the cytokine osteopontin (OPN). OPN has been implicated in virulent asthma, and OPN knockout mice do not develop osteoporosis. As we have pursued whole animal studies with astrogorgiadiol, we have increased the scale of the synthesis. We report an improved preparation of the A-ring synthon and the scale-up of the diasteromerically pure D-ring/sidechain chiron.