217468-55-8Relevant academic research and scientific papers
A novel method for the synthesis of phenanthrenes and benzo[a]carbazoles
De Koning, Charles B.,Michael, Joseph P.,Rousseau, Amanda L.
, p. 8725 - 8728 (1998)
The synthesis of several phenanthrenes and carbazoles utilising a novel reaction mediated by potassium t-butoxide and light through a quartz filter is described.
A copper(ii)-catalyzed annulative formylation of o-alkynylanilines with DMF: a single-step strategy for 3-formyl indoles
Ganesan, Balaji,Senadi, Gopal Chandru,Guo, Bing-Chun,Hung, Min-Yuan,Lin, Wei-Yu
, p. 40968 - 40973 (2019/01/03)
In this paper, a copper(ii)-catalyzed reaction of o-alkynylanilines with dimethylformamide (DMF) in the presence of oxygen has been developed for synthesizing multisubstituted 3-formyl indole scaffolds. This one-pot reaction proceeds through a cascade 5-endo-dig cyclization followed by formylation to construct 1,2-disubstituted 3-formyl indoles. The key aspects of this synthesis method are the broad substrate scope (with 38 examples), and well tolerating various functional groups. In addition, a detailed mechanism has been proposed, where DMF may serve as a carbon source for the in situ C3 formylation of the obtained indole derivatives.
A versatile and convenient method for the synthesis of substituted benzo[a]carbazoles and pyrido[2,3-a]carbazoles
De Koning, Charles B.,Michael, Joseph P.,Rousseau, Amanda L.
, p. 1705 - 1713 (2007/10/03)
Treatment of 2-(o-tolyl)- or 2-(3-methyl-2-pyridyl)-substituted indole-3-carbaldehydes with potassium tert-butoxide in DMF at 70-80°C with simultaneous irradiation from a 400 W high-pressure mercury lamp afforded benzo[a]carbazoles and pyrido[2,3-a]carbaz
