217476-92-1

Basic information

• Product Name: (2S,3R,4aR,9aR)-7-[(E)-2-{4-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3,5-dihydroxyphenyl}ethenyl]-1,1,4a-trimethyl-2,3,4,4a,9,9a-hexahydro-1H-xanthene-2,3,5-triol
• Synonyms: (2S,3R,4aR,9aR)-7-((E)-2-{4-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3,5-dihydroxyphenyl}vinyl)-1,1,4a-trimethyl-2,3,4,4a,9,9a-hexahydro-1H-xanthene-2,3,5-triol; (2S,3R,4aR,9aR)-7-[(E)-2-{4-[(2E)-3,7-Dimethylocta-2,6-dien-1-yl]-3,5-dihydroxyphenyl}vinyl]-1,1,4a-trimethyl-2,3,4,4a,9,9a-hexahydro-1H-xanthene-2,3,5-triol; 1H-xanthene-2,3,5-triol, 7-[(E)-2-[4-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,5-dihydroxyphenyl]ethenyl]-2,3,4,4a,9,9a-hexahydro-1,1,4a-trimethyl-, (2S,3R,4aR,9aR)-; 1H-xanthene-2,3,5-triol, 7-[(E)-2-[4-[(2E)-3,7-dimethyl-2,6-octadienyl]-3,5-dihydroxyphenyl]ethenyl]-2,3,4,4a,9,9a-hexahydro-1,1,4a-trimethyl-, (2S,3R,4aR,9aR)-
• CAS NO: 217476-92-1
• Molecular Formula: C₃₄H₄₄O₆
• Molecular Weight: 548.7096
• Mol File: 217476-92-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 732.4°C at 760 mmHg
• Flash Point: 396.7°C
• Density: 1.201g/cm³
• Vapor Pressure: 1.62E-22mmHg at 25°C
• Refractive Index: 1.633
• CAS DataBase Reference: (2S,3R,4aR,9aR)-7-[(E)-2-{4-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3,5-dihydroxyphenyl}ethenyl]-1,1,4a-trimethyl-2,3,4,4a,9,9a-hexahydro-1H-xanthene-2,3,5-triol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R,4aR,9aR)-7-[(E)-2-{4-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3,5-dihydroxyphenyl}ethenyl]-1,1,4a-trimethyl-2,3,4,4a,9,9a-hexahydro-1H-xanthene-2,3,5-triol(217476-92-1)
• EPA Substance Registry System: (2S,3R,4aR,9aR)-7-[(E)-2-{4-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3,5-dihydroxyphenyl}ethenyl]-1,1,4a-trimethyl-2,3,4,4a,9,9a-hexahydro-1H-xanthene-2,3,5-triol(217476-92-1)

Safety Data

• Hazardous Substances Data: 217476-92-1(Hazardous Substances Data)

Upstream product

• 1263362-58-8 C₁₆H₁₅BrO₄ 
• 1263362-61-3 C₁₅H₁₅BrO₃ 
• 1263362-03-3 C₁₆H₁₇BrO₃ 
• 1263362-04-4 C₂₆H₃₄O₄ 
• 1263362-07-7 C₁₉H₂₈O₄ 
• 1263362-08-8 C₁₉H₂₆O₄ 
• 1263362-09-9 C₁₈H₂₆O₄ 
• 1263362-10-2 C₂₀H₃₀O₅ 
• 1263362-11-3 C₂₀H₂₈O₅ 
• 1263362-14-6 C₂₇H₃₆O₇ 
• 1263362-15-7 C₂₀H₂₈O₆ 
• 1263362-16-8 C₂₀H₃₀O₆ 
• 1263362-17-9 C₁₉H₂₆O₆ 
• 1263362-18-0 C₂₃H₃₄O₈ 

Relevant articles and documents

Exploration of Cascade Cyclizations Terminated by Tandem Aromatic Substitution: Total Synthesis of (+)-Schweinfurthin A

The termination of epoxide-initiated cascade cyclizations with a range of "protected" phenols is described. When the protecting group can be lost as a stabilized electrophile, the cascade process continues beyond ring closure to afford products which have undergone a tandemelectrophilic aromatic substitution. A number of groups have proven viable in this process and the regiochemistry of their substitution reactions has been studied. Application of this methodology in the first total synthesis of (+)-schweinfurthin A, a potent antiproliferative agent, has been achieved.