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N-(toluene-4-sulfonyl)-L-serine hydrazide is a chemical compound with the molecular formula C11H14N2O4S. It is a derivative of L-serine, an amino acid, with a toluene-4-sulfonyl group attached to the nitrogen atom and a hydrazide group at the carboxylic acid end. N-(toluene-4-sulfonyl)-L-serine hydrazide is often used in organic synthesis and as a reagent in various chemical reactions, particularly in the formation of peptide bonds. It is also known for its potential applications in the development of pharmaceuticals and as a building block for more complex molecules. The compound is characterized by its white crystalline appearance and is soluble in common organic solvents.

21752-11-4

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21752-11-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 21752-11-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,7,5 and 2 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 21752-11:
(7*2)+(6*1)+(5*7)+(4*5)+(3*2)+(2*1)+(1*1)=84
84 % 10 = 4
So 21752-11-4 is a valid CAS Registry Number.

21752-11-4Relevant academic research and scientific papers

Synthesis and antiviral activities of novel acylhydrazone derivatives targeting HIV-1 capsid protein

Tian, Baohe,He, Meizi,Tang, Shixing,Hewlett, Indira,Tan, Zhiwu,Li, Jiebo,Jin, Yinxue,Yang, Ming

scheme or table, p. 2162 - 2167 (2009/12/25)

HIV-1 capsid protein (CA) plays important roles in the viral replication cycle. A number of acylhydrazone derivatives that act as inhibitors of HIV-1 CA assembly, were designed and synthesized. The synthesized compounds were tested for their antiviral activities and cytotoxicities using CEM cells. Some derivatives also were assayed for their ability to inhibit HIV-1 CA assembly in vitro. Among them, compounds 14f and 14i display the most promising potency with EC50 values of 0.21 and 0.17 μΜ, respectively.

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