21752-32-9

Basic information

• Product Name: L-Methionine [S]-Sulfoximine
• Synonyms: L-Methionine [S]-Sulfoximine;(2S)-2-AMino-4-[[S(S)]-S-MethylsulfoniMidoyl]butanoic Acid;(S)-L-S-(3-aMino-3-carboxypropyl)-S- MethylsulfoxiMine;[S-(R*,R*)]-2-AMino-4- (S-MethylsulfoniMidoyl)butanoic Acid
• CAS NO: 21752-32-9
• Molecular Formula: C₅H₁₂N₂O₃S
• Molecular Weight: 180.22538
• Product Categories: Amino Acids & Derivatives;Chiral Reagents;Sulfur & Selenium Compounds
• Mol File: 21752-32-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 218-226°C (dec.)
• Boiling Point: 352.2±52.0 °C(Predicted)
• Appearance: /
• Density: 1.46±0.1 g/cm3(Predicted)
• Storage Temp.: Refrigerator
• Solubility: Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: L-Methionine [S]-Sulfoximine(CAS DataBase Reference)
• NIST Chemistry Reference: L-Methionine [S]-Sulfoximine(21752-32-9)
• EPA Substance Registry System: L-Methionine [S]-Sulfoximine(21752-32-9)

Safety Data

• Hazardous Substances Data: 21752-32-9(Hazardous Substances Data)

Usage

Chemical Properties

White to Off-White Solid

Uses

It is the diastereoisomer of L-Methionine [R,S]-Sulfoximine (M260500) that inhibits glutamine synthetase.

Upstream product

• 15985-39-4 L-methionine sulfoximine 
• 87173-45-3 2-((1R,4R)-1-Methyl-1,3-dioxo-3,4,5,6-tetrahydro-1λ⁶-[1,2]thiazin-4-yl)-isoindole-1,3-dione 
• 87141-35-3 C₁₃H₁₄N₂O₅S 
• 21056-59-7 L-methionine-S,R-sulfoximine 
• 87173-46-4 2-((1S,4R)-1-Methyl-1,3-dioxo-3,4,5,6-tetrahydro-1λ⁶-[1,2]thiazin-4-yl)-isoindole-1,3-dione 

Relevant articles and documents

Absolute configuration of L-methionine sulfoximine as a toxic principle in Cnestis palala (Lour.) Merr.

An unusual amino acid, L-methionine sulfoximine (1), has been isolated from the fresh seeds of Cnestis palala (Lour.) Merr. [Connaraceae]. The absolute configuration of the natural sulfoximine (1) was confirmed to be 2(S)-methionine S(S)-sulfoximine [(2S,SS)-2-amino-4-(S-methylsulfonimidoyl)-n-butanoic acid] by comparison of the [α](D) value and IR spectrum with those of authentic samples obtained through the optical resolution of synthetic materials. Acute toxicity of the seeds of C. palala in a beagle dog was also studied.