21758-10-1Relevant academic research and scientific papers
(E)-Selective Horner-Wadsworth-Emmons reaction of aryl alkyl ketones with bis(2,2,2-trifluoroethyl)phosphonoacetic acid
Sano, Shigeki,Takemoto, Yuka,Nagao, Yoshimitsu
, p. 8853 - 8855 (2007/10/03)
The stereoselective Horner-Wadsworth-Emmons reaction of aryl alkyl ketones with bis(2,2,2-trifluoroethyl)phosphonoacetic acid utilizing lithium hexamethyldisilazide in DMF afforded (E)-α,β-unsaturated carboxylic acids as the major products.
