21762-74-3

Usage

Uses

Used in Pharmaceutical Industry:
6-Nitro-2H-benzo[b][1,4]thiazin-3(4H)-one is used as a pharmaceutical compound for its antimicrobial and anti-inflammatory properties. It has potential applications in the development of new drugs targeting various diseases and conditions.
Used in Agrochemical Industry:
6-Nitro-2H-benzo[b][1,4]thiazin-3(4H)-one is used as an agrochemical compound for its potential applications in pest control and crop protection. It can be utilized in the development of new pesticides and herbicides to improve agricultural productivity.
Used in Materials Sciences:
6-Nitro-2H-benzo[b][1,4]thiazin-3(4H)-one is used as a material in the development of new fluorescent probes and heterocyclic compounds. Its unique physical and chemical properties make it an important chemical for further research and development in the field of organic and medicinal chemistry.

Upstream product

• 32403-69-3 2-(2,4-dinitrophenylthio)acetic acid 
• 90221-50-4 N-(2-bromo-5-nitrophenyl)acetamide 
• 68-11-1 mercaptoacetic acid 
• 79-11-8 chloroacetic acid 
• 369-36-8 6-fluoro-3-nitroaniline 
• 2365-48-2 Methyl thioglycolate 
• 6283-25-6 H₂NC₆H₃(Cl)NO₂ 
• 623-51-8 ethyl 2-sulfanylacetate 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 7686-29-5 2-amino-4-nitrobenzenethiol 

Downstream Products

• 385442-59-1 6-benzoylamino-4-butyl-2H-benzo[1,4]thiazin-3-one 
• 385442-62-6 6-benzoylbutylamino-4-butyl-2H-benzo[1,4]thiazin-3-one 
• 385442-63-7 6-benzoyloctylamino-4-butyl-2H-benzo[1,4]thiazin-3-one 
• 99286-76-7 8-Nitro-1-phenyl-4H-5-thia-2,3,9b-triaza-cyclopenta[a]naphthalene 
• 99286-59-6 Benzoic acid N'-(6-nitro-2H-benzo[1,4]thiazin-3-yl)-hydrazide 
• 21762-78-7 6-amino-2H-1,4-benzothiazin-3(4H)-one 
• 1193387-98-2 6-nitro-3,4-dihydro-2H-benzo[b][1,4]thiazine 

Relevant academic research and scientific papers

TRIAZINONE COMPOUNDS

The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treati

HETEROCYCLIC COMPOUNDS AND THEIR USES

Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, including but not restricted to autoimmune diseases such as systemic lupus erythematosis (SLE), myestenia gravis, rheumatoid arthritis, acute disseminated encephalomyelitis, idiopathic thrombocytopenic purpura, multiples sclerosis, Sjoegren's syndrome and autoimmune hemolytic anemia, allergic conditions including all forms of hypersensitivity, The present invention also enables methods for treating cancers that are mediated, dependent on or associated with p110 activity, including but not restricted to leukemias, such as Acute Myeloid leukaemia (AML) Myelo-dysplastic syndrome (MDS) myelo-proliferative diseases (MPD) Chronic Myeloid Leukemia (CML) T-cell Acute Lymphoblastic leukaemia ( T-ALL) B-cell Acute Lymphoblastic leukaemia (B-ALL) Non Hodgkins Lymphoma (NHL) B-cell lymphoma and solid tumors, such as breast cancer.

CYCLOHEXYL OR PIPERIDINYL CARBOXAMIDE ANTIBIOTIC DERIVATIVES

The invention relates to antibiotic cyclohexyl or piperidinyl carboximide derivatives of formula (I) wherein R1 represents hydrogen, halogen, (C1-C4)alkyl, (C1-C4)alkoxy, cyano or COOR2, R2 being (C1-C4)alkyl;one or two of U, V, W and X represent(s) N and the remaining represent each CH, or, in the case of X, may also represent CRX, RX being a halogen atom;either B represents N and A represents CH2CH2 or CH(OR3)CH2, or B represents CH or C(OR4) and A represents OCH2, CH2CH(OR5), CH(OR6)CH2, CH(OR7)CH(OR8), CH═CH or CH2CH2;each of R3, R4, R5, R6, R7, and R8 represents independently hydrogen, SO3H, PO3H2, CH2OPO3H2 or COR9, R9 being either CH2CH2COOH or such that R9—COOH is naturally occurring amino acid or dimethylaminoglycine;and to salts of such compounds of formula (I).

COMPOUNDS AND METHODS OF USE

Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Alpha2C adrenoreceptor agonists

In its many embodiments, the present invention relates to a novel class of phenylmorpholine and phenylthiomorpholine compounds useful as α2C adrenergic receptor agonists, pharmaceutical compositions containing the compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the α2C adrenergic receptor agonists using such compounds or pharmaceutical compositions.

Synthesis and structural study of substituted arylideneimidazolidines and arylidenebenzothiazines

Synthesis and physico-chemical properties of six 5-arylidene-3-benzyl-1- methyl-2-thioxoimidazolidin-4-ones and three 2-arylidene-6-nitro-2H-1,4- benzothiazin-3(4H)-ones have been described. These new compounds were synthetised by Knoevenagel condensation