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EUPATORIN-5-METHYL ETHER is a natural compound derived from the Orthosiphon stamineus plant, which is native to Malaysia. It is a flavonoid with a methyl ether group attached to its structure, giving it unique chemical and biological properties. EUPATORIN-5-METHYL ETHER is known for its potent antioxidant and anti-inflammatory activities, making it a valuable component in various applications.

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  • 21764-09-0 Structure
  • Basic information

    1. Product Name: EUPATORIN-5-METHYL ETHER
    2. Synonyms: 3'-HYDROXY-5,6,7,4'-TETRAMETHOXYFLAVONE;3-HYDROXY-5,6,7,4'-TETRAMETHOXYFLAVONE;3-HYDROXY-5,6,7,4-TETRAMETHOXYFLAVONE;3'-HYDROXY-4',5,6,7-TETRAMETHOXYFLAVONE;EUPATORIN-5-METHYL ETHER;Eupatorin methyl ether;Eupatorinemethylether;3''-HYDROXY-4'',5,6,7-TETRAMETHOXYFLAVONE 97%
    3. CAS NO:21764-09-0
    4. Molecular Formula: C19H18O7
    5. Molecular Weight: 358.34
    6. EINECS: N/A
    7. Product Categories: Penta-substituted Flavones;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
    8. Mol File: 21764-09-0.mol
  • Chemical Properties

    1. Melting Point: 179-180°C
    2. Boiling Point: 573.7°Cat760mmHg
    3. Flash Point: 207.4°C
    4. Appearance: /
    5. Density: 1.309g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: Refrigerator, under inert atmosphere
    8. Solubility: DMSO (Slightly), Methanol (Slightly)
    9. PKA: 9.99±0.10(Predicted)
    10. CAS DataBase Reference: EUPATORIN-5-METHYL ETHER(CAS DataBase Reference)
    11. NIST Chemistry Reference: EUPATORIN-5-METHYL ETHER(21764-09-0)
    12. EPA Substance Registry System: EUPATORIN-5-METHYL ETHER(21764-09-0)
  • Safety Data

    1. Hazard Codes: T
    2. Statements: 25
    3. Safety Statements: 45
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 21764-09-0(Hazardous Substances Data)

21764-09-0 Usage

Uses

Used in Pharmaceutical Industry:
EUPATORIN-5-METHYL ETHER is used as a therapeutic agent for its potent antioxidant and anti-inflammatory properties. It can be employed in the development of drugs targeting various inflammatory and oxidative stress-related diseases, such as arthritis, asthma, and neurodegenerative disorders.
Used in Cosmetic Industry:
EUPATORIN-5-METHYL ETHER is used as an active ingredient in cosmetic products for its antioxidant and anti-inflammatory effects. It can help protect the skin from environmental stressors, such as UV radiation and pollution, and reduce the signs of aging, making it a valuable addition to skincare formulations.
Used in Nutraceutical Industry:
EUPATORIN-5-METHYL ETHER is used as a dietary supplement for its antioxidant properties. It can be incorporated into nutraceutical products to support overall health and well-being by neutralizing free radicals and reducing oxidative stress in the body.
Used in Food and Beverage Industry:
EUPATORIN-5-METHYL ETHER can be used as a natural preservative in the food and beverage industry due to its antioxidant properties. It can help extend the shelf life of products by preventing oxidation and spoilage, maintaining their freshness and quality.
Used in Antioxidant Research:
EUPATORIN-5-METHYL ETHER is used as a subject of study in antioxidant research to better understand its potential applications and mechanisms of action. This research can lead to the development of new drugs and therapies for various diseases and conditions related to oxidative stress.

Check Digit Verification of cas no

The CAS Registry Mumber 21764-09-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,7,6 and 4 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 21764-09:
(7*2)+(6*1)+(5*7)+(4*6)+(3*4)+(2*0)+(1*9)=100
100 % 10 = 0
So 21764-09-0 is a valid CAS Registry Number.

21764-09-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(3-hydroxy-4-methoxyphenyl)-5,6,7-trimethoxychromen-4-one

1.2 Other means of identification

Product number -
Other names Eupatorin 5-Methyl Ether

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:21764-09-0 SDS

21764-09-0Downstream Products

21764-09-0Relevant articles and documents

Identification and Quantification of Both Methylation and Demethylation Biotransformation Metabolites of 5-Demethylsinensetin in Rats

Wang, Xiaoqi,Li, Dongli,Cao, Yong,Ho, Chi-Tang,Huang, Qingrong

, p. 3162 - 3171 (2022/03/16)

5-Demethylated polymethoxyflavones (5-OH PMFs) are the most unique monodemethylated PMFs with relatively low polarities and are proved to possess better anticancer and anti-inflammatory effects than their respective permethoxylated ones. However, their de

The total synthesis of an aurone isolated from Uvaria hamiltonii: Aurones and flavones as anticancer agents

Lawrence, Nicholas J.,Rennison, David,McGown, Alan T.,Hadfield, John A.

, p. 3759 - 3763 (2007/10/03)

The naturally occurring aurone 1, isolated from Uvaria hamiltonii, and a series of aurones analogues based structurally on known tubulin binding agents were prepared and evaluated for anticancer activity. Aurone 20 was the most active (IC50 K562 50 nM) and caused significant G2/M cell-cycle arrest.

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