217649-77-9

Upstream product

• 676-88-0 dimethyl(methylthio)sulfonium tetrafluoroborate 
• 371193-61-2 carbonic acid benzyl ester 4-dimethylamino-2-[2-ethyl-3,4,10-trihydroxy-13-(4-methoxy-4,6-dimethyl-5-oxo-tetrahydro-pyran-2-yloxy)-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-aza-cyclopentadec-11-yloxy]-6-methyl-tetrahydro-pyran-3-yl ester 
• 501-53-1 benzyl chloroformate 
• 352032-78-1 (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-2-O-[(phenylmethoxy)carbonyl]-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one 
• 76801-85-9 9-Deoxo-9a-aza-9a-homoerythromycin A 
• 2181-42-2 trimethylsulphonium iodide 
• 3084-53-5 trimethylsulphonium bromide 

Downstream Products

• 217500-96-4 (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[[2,6-dideoxy-3-C-methyl-3-Ο-methyl-4-C-[(propylamino)methyl]-α-L-ribohexopyranosyl]oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylohexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one 

Relevant academic research and scientific papers

Method for synthesizing oxytetracycline and oxytetracycline phosphate (by machine translation)

Step A product shown in Formula is obtained by dissolving, a product of: Formula I with a product shown by subjecting a product shown II in Formula to a reaction; to obtain a product having a hydroxyl: protection product II as shown in Formula I, and a ca

METHOD AND INTERMEDIATE FOR PREPARING TULATHROMYCIN

A method and an intermediate for preparing a tulathromycin. The method includes the following step: in an organic solvent, subjecting a compound represented by formula (II) and an n-propylamine to a ring-opening addition shown below to obtain a tulathromycin represented by formula (I), wherein the organic solvent is a 1,2-propandiol. Tulathromycin obtained using the method has a high purity, with an HPLC purity being 95% and above, and up to 99% and above, satisfying a required purity for preparing a tulathromycin as a pharmaceutical formulation. The method has a high yield, is simple to operate, and is more suitable for industrial production.

Synthesis, stereochemical assignment and biological activity of a novel series of C-4″ modified aza-macrolides

Modification of the cladinose C-4″ position via manipulation of the corresponding keto derivatives afforded two stereochemically pure series of compounds. The synthesis and structure determination of these compounds is described within. The in vitro and i

Synthesis and activity of a novel class of tribasic macrocyclic antibiotics: The triamilides

The stereoselective synthesis of two novel series of tribasic macrocyclic antibiotics with potent in vitro activity against Pasteurella multocida and Escherichia coli strains of bacteria is described. The in vitro activity can be significantly influenced