217658-62-3

Upstream product

• 873923-41-2 (2R)-2-fluoro-2-hydroxymethyl-4-penten-1-yl benzoate 
• 108-24-7 acetic anhydride 
• 93-97-0 benzoic acid anhydride 
• 217658-49-6 (2S)-2-fluoro-2-(benzyloxymethyl)-4-penten-1-yl benzoate 
• 217658-45-2 (2R)-2-hydroxy-2-(benzyloxymethyl)-4-penten-1-yl benzoate 

Downstream Products

• 217658-78-1 (+)-N⁴-acetyl-1-(3'-O-benzoyl-2,3-dideoxy-3-fluoroapio-β-D-furanosyl)cytosine 
• 217658-82-7 (-)-N⁴-acetyl-1-(3'-O-benzoyl-2,3-dideoxy-3-fluoroapio-α-D-furanosyl)cytosine 
• 217659-31-9 (-)-1-(3'-O-benzoyl-2,3-dideoxy-3-fluoroapio-β-D-furanosyl)thymine 
• 217659-34-2 (-)-1-(3'-O-benzoyl-2,3-dideoxy-3-fluoroapio-α-D-furanosyl)thymine 

Relevant academic research and scientific papers

Asymmetric synthesis of 2′,3′-dideoxy-3′- fluoroapiofuranosyl nucleosides

An efficient stereoselective synthetic method for each stereoisomer of enantiomerically pure 2′,3′-dideoxy-3′-fluoroapiofuranosyl nucleosides was developed. The key features of this strategy are the enantiospecific fluorination of the tert-alcohol and the