21769-32-4Relevant academic research and scientific papers
New analogues of butylated hydroxytoluene as anti-inflammatory and antioxidant agents
Ziakas, George N.,Rekka, Eleni A.,Gavalas, Antonios M.,Eleftheriou, Phaedra T.,Kourounakis, Panos N.
, p. 5616 - 5624 (2006)
Amine or amide derivatives bearing the 2,6-di-tert-butyl phenol moiety are synthesised. Almost all are antioxidants, reduce acute inflammation and inhibit COX-1 and lipoxygenase activity. The most potent anti-inflammatory, COX-1 inhibitor and antioxidant agent, with low toxicity, is 2,6-di-tert-butyl-4-thiomorpholin-4-ylmethyl-phenol.
Synthesis and characterization of new 4-alkyl-2-arylmorpholin-2-ol hydrochlorides
Mancilla, Teresa,Zamudio-Rivera, Luis S.,Beltran, Hiram I.,Carrillo, Lourdes,Farfan, Norberto
, p. 357 - 369 (2007/10/03)
The synthesis of 4-alkyl-2-arylmorpholin-2-ol hydrochlorides by diastereoselective reaction of 2-bromoacetophenones with β-aminoalcohols has been accomplished. Copyright Taylor & Francis, Inc.
