2177-98-2Relevant academic research and scientific papers
Selection of surfactant-modified lipases for interesterification of triglyceride and fatty acid
Mogi, Ken-Ichi,Nakajima, Mitsutoshi
, p. 1505 - 1512 (1996)
Interesterification of tripalmitin and stearic acid in n-hexane was investigated with surfactant-modified lipases. Various kinds of lipases and surfactants were screened for high interesterification activity of the modified lipases. The modified-lipase activity was influenced by both the lipases and the hydrophile-lipophile balance value and fatty acid group of the surfactants. The modified lipase obtained from Rhizopus japonicus with sorbitan monostearate as surfactant had the highest activity in the n-hexane system. The interesterification activity of the selected modified lipase in molten substrates at 75°C without solvents was the same as that in the n-hexane system at 40°C.
Synthesis of Triglycerides from 1,3-Dibromopropan-2-ol
Bhati, Asharam,Hamilton, Richard J.,Steven, David A.,Aneja, Rajender,Padley, Frederick B.
, p. 1553 - 1558 (2007/10/02)
1,3-Dibromopropan-2-ol (I) was converted into an acyl derivative (VI) by reaction with an appropriate acyl chloride in the presence of pyridine.The acyl derivative (VI) was subjected to nucleophilic substitution with 3 mol. equiv. tris(decyl)methylammonium carboxylate in refluxing hexane.This led to symmetrical diacid triglycerides in 90-94percent yield.Substitution with an equimolar amount of the carboxylate afforded, predominantly, the 1,2-bisacyloxy-3-bromopropane (VII) which could be easily isolated and further substituted to give unsymmetrical diacid- and triacid-triglycerides in ca. 96percent yield.Lipolysis showed the synthetic triglycerides to be ca. 99percent pure.
