2179-24-0Relevant academic research and scientific papers
Selective separation of mono glyceryl ferulate using water from an ionic liquid solution of enzymatic transesterification
Sun, Shangde,Chen, Xiaowei,Bi, Yanlan,Yang, Guolong
, p. 1339 - 1345 (2014)
Mono glyceryl ferulate (MFG), an all-natural derivative of ferulic acid, can be used as antioxidant and a UV filter in food and cosmetic formulations. However, the applications of MFG in these fields are limited due to its low availability in nature. In this work, a novel method for selective separation of MFG from a room temperature ionic liquid (RTIL) solution of enzymatic transesterification of ethyl ferulate with glycerol was investigated. The effects of different extractants and extraction conditions on the selective separation of MFG were also studied. High extraction yields of MFG (98.23 ± 1.09 %) and the relative content of MFG in the extracts (97.76 ± 1.25 %) were achieved using neutral deionized water as extractant under the following conditions: 0.5:1 volume ratio of water to RTIL solution, extraction time of 6 min, centrifugation time of 6 min, and extraction done eight times. The extraction thermodynamics showed that the extraction of MFG was an exothermic process. The purified MFG exhibited good UV adsorbing properties at 280-360 nm with a λ max at 322 nm.
Ultrasonic-promoted enzymatic preparation, identification and multi-active studies of nature-identical phenolic acid glycerol derivatives
Dong, Zhe,Liu, Zengshe,Sun, Teng,Zhang, Haiping,Zheng, Mingming
, p. 11139 - 11147 (2020/04/03)
Phenolic acid glycerols (PAGs) are a group of rare phytochemicals found from potato periderm, which show great potential in the food, cosmetic and pharmaceutical industries. In this study, seven PAGs were enzymatically synthesized via transesterification of ethyl phenates (EPs) with glycerol by ultrasonic promotion. The conversions of 88.1-98.5% could be obtained in 1-9 h. Compared with the conventional stirring methods, the catalytic efficiency was significantly increased 11.0-44.0 folds by ultrasound assistance. The lipid peroxidation inhibition activity increased 8.1-fold and 14.4-fold compared to the parent phenolic acids (PAs). Furthermore, caffeoyl glycerol and feruloyl glycerol exhibited excellent antimicrobial activity against Escherichia coli compared to the corresponding PAs with minimum inhibitory concentration (MIC) decreasing 4-16-fold. The PAGs can also absorb a much wider and higher amount of the harmful UV-B rays than the corresponding PAs. The present strategy for facile synthesis of multifunctional PAGs paves the way for the development and application of natural phytochemicals and novel ingredients.
