217942-85-3

Basic information

• Product Name: 3-(2-chlorophenyl)-6-fluoro-2-thioxo-2,3-dihydro-1H-quinazolin-4-one
• Synonyms: 3-(2-chlorophenyl)-6-fluoro-2-thioxo-2,3-dihydro-1H-quinazolin-4-one
• CAS NO: 217942-85-3
• Molecular Weight: 306.748
• Mol File: 217942-85-3.mol

Chemical Properties

• CAS DataBase Reference: 3-(2-chlorophenyl)-6-fluoro-2-thioxo-2,3-dihydro-1H-quinazolin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-chlorophenyl)-6-fluoro-2-thioxo-2,3-dihydro-1H-quinazolin-4-one(217942-85-3)
• EPA Substance Registry System: 3-(2-chlorophenyl)-6-fluoro-2-thioxo-2,3-dihydro-1H-quinazolin-4-one(217942-85-3)

Safety Data

• Hazardous Substances Data: 217942-85-3(Hazardous Substances Data)

Upstream product

• 2740-81-0 2-chlorophenylisothiocyanate 
• 446-08-2 2-amino-5-fluorobenzoic acid 

Downstream Products

• 346700-97-8 2-chloro-3-(2-chlorophenyl)-6-fluoro-3H-quinazolin-4-one 

Relevant articles and documents

Quinazolin-4-one AMPA antagonists

The present invention relates to novel quinazolin-4-one derivatives of the formula wherein A is a benzo or thieno fused aromatic ring; B is phenyl, pyridyl or pyrimidyl; X is N or CH; and Y-Z is —CH2NH— or —NHCH2—; and to pharmaceuti

Quinazolin-4-one α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists: Structure-activity relationship of the C-2 side chain tether

A series of 6-fluoro-3-(2-chlorophenyl)quinazolin-4-ones has been prepared, which contains a 2-fluorophenyl ring attached to C-2 by a variety of two-atom tethers. These compounds were used to probe the structure-activity relationship (SAR) for AMPA recept