217974-64-6Relevant academic research and scientific papers
Conversion of N-Acyl-4-acyloxy-β-lactams into 1,3-oxazin-6-ones: Two consecutive pseudopericyclic processes
Alajarín, Mateo,Vidal, Angel,Sánchez-Andrada, Pilar,Tovar, Fulgencio,Ochoa, Ginés
, p. 965 - 968 (2000)
(equation presented) N-Acyl-4-acyloxy-β-lactams are converted into 1,3-oxazin-6-ones under basic conditions. This transformation is believed to proceed via N-acylazetones, which rearrange to the final products by a sequence of two electrocyclic processes. The calculated (RHF and B3LYP) transrtion structures of both concerted reactions are shown to present characteristic pseudopericyclic orbital topologies.
The first aza-Wittig reaction of the β-lactam carbonyl group
Alajarín, Mateo,Molina, Pedro,Vidal, ángel,Tovar, Fulgencio
, p. 1288 - 1290 (2007/10/03)
The imination of the β-lactam carbonyl group by the aza-Wittig reaction is described. The process is only amenable when carried out intramolecularly.
