21801-89-8 Usage
Uses
Used in Public Health Awareness:
3-Carbamoyl-2-methylimidazo(1,2-a)pyridine is used as a subject of public health awareness campaigns to educate consumers about the potential risks associated with consuming cooked meats that have been prepared at high temperatures. The aim is to promote healthier cooking practices, such as using lower cooking temperatures and avoiding charred or well-done meats, to reduce exposure to CMIP and mitigate the potential health risks.
Used in Research and Development:
In the field of food safety and nutrition, 3-Carbamoyl-2-methylimidazo(1,2-a)pyridine is used as a research subject to study its formation mechanisms, genotoxic effects, and potential mitigation strategies. This research is crucial for developing methods to reduce CMIP levels in cooked foods and for understanding its impact on human health.
Used in Regulatory Frameworks:
3-Carbamoyl-2-methylimidazo(1,2-a)pyridine is used as a reference compound in regulatory frameworks and guidelines for food safety. It serves as a basis for setting acceptable exposure limits and for monitoring the presence of potentially harmful compounds in food products, ensuring that the food industry adheres to safety standards to protect public health.
Used in Food Industry:
3-Carbamoyl-2-methylimidazo(1,2-a)pyridine is used as a parameter in the food industry for quality control and product development. Manufacturers may monitor the levels of CMIP in their products to ensure compliance with safety regulations and to develop cooking methods or product formulations that minimize the formation of this potentially harmful compound.
Check Digit Verification of cas no
The CAS Registry Mumber 21801-89-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,8,0 and 1 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 21801-89:
(7*2)+(6*1)+(5*8)+(4*0)+(3*1)+(2*8)+(1*9)=88
88 % 10 = 8
So 21801-89-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3O/c1-6-8(9(10)13)12-5-3-2-4-7(12)11-6/h2-5H,1H3,(H2,10,13)
21801-89-8Relevant academic research and scientific papers
2-Aminopyridines as an α-Bromination Shuttle in a Transition Metal-Free One-Pot Synthesis of Imidazo[1,2-a]pyridines
Roslan, Irwan Iskandar,Ng, Kian-Hong,Chuah, Gaik-Khuan,Jaenicke, Stephan
supporting information, p. 364 - 369 (2016/04/26)
A wide range of imidazo[1,2-a]pyridines are accessible from cheap and readily available 2-aminopyridines and 1,3-dicarbonyl compounds using a unique CBrCl3/2-aminopyridine system for bromination at the α-carbon. 2-Aminopyridine is not only the substrate but also acts as a bromination shuttle, transferring the bromine atom from CBrCl3 to the α-carbon of the 1,3-dicarbonyl. The reaction mechanism involves a series of reversible steps, including an addition reaction with cyclic transition state, to form a bromo-hemiaminal intermediate. Isolated yields of up to 97% were obtained under mild conditions and at short reaction times in this transition metal-free, one-pot synthesis.
HETEROARYLS AND THEIR USE AS PI3K INHIBITORS
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Page/Page column 321-322, (2010/08/18)
This invention provides compounds of formula (IA) or (IB): wherein R1, R2, G1 and HY are as described in the specification. The compounds are inhibitors of PI3K and/or mTor and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
