21820-51-9 Usage
Chemical Properties
White Solid
Uses
Different sources of media describe the Uses of 21820-51-9 differently. You can refer to the following data:
1. Useful in the study of tyrosine-phosphorylation, which has been linked with the malignant transformation of cells by some RNA tumour viruses.
2. O-Phospho-L-tyrosine is used in the study of tyrosine-phosphorylation, which has been linked to the malignant transformation of cells by various RNA tumor viruses. Plays a role in signal transduction.
Definition
ChEBI: A non-proteinogenic L-alpha-amino acid that is L-tyrosine phosphorylated at the phenolic hydroxy group.
Purification Methods
Purify it by recrystallisation from H2O or H2O/EtOH. [Levene & Schormüller J Biol Chem 100 583 1933, Posternak & Graff Helv Chim Acta 28 1258 1945, Beilstein 14 III 1510.]
Check Digit Verification of cas no
The CAS Registry Mumber 21820-51-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,8,2 and 0 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 21820-51:
(7*2)+(6*1)+(5*8)+(4*2)+(3*0)+(2*5)+(1*1)=79
79 % 10 = 9
So 21820-51-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H12NO6P/c11-7-3-1-6(2-4-7)5-8(9(12)13)10-17(14,15)16/h1-4,8,11H,5H2,(H,12,13)(H3,10,14,15,16)
21820-51-9Relevant articles and documents
A Simple Preparation of O-Phospho-L-tyrosine
Alewood, Paul F.,Johns, R. B.,Valerio, Robert M.,Kemp, Bruce E.
, p. 30 - 31 (1983)
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Enzymatically Forming Intranuclear Peptide Assemblies for Selectively Killing Human Induced Pluripotent Stem Cells
He, Hongjian,Liu, Shuang,Lu, Shijiang,Shy, Adrianna N.,Xu, Bing,Yi, Meihui,Zhang, Qiuxin
supporting information, p. 15852 - 15862 (2021/10/02)
Tumorigenic risk of undifferentiated human induced pluripotent stem cells (iPSCs), being a major obstacle for clinical application of iPSCs, requires novel approaches for selectively eliminating undifferentiated iPSCs. Here, we show that an l-phosphopenta
Modified synthesis method of oxidative phosphorylation-L-tyrosine
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Paragraph 0022-0023; 0025-0026; 0028-0029; 0030-0032, (2019/01/14)
The invention discloses a modified synthesis method of oxidative phosphorylation-L-tyrosine, and belongs to the field of organic chemistry. L-tyrosine and phosphorus pentoxide are reacted in 85% strong phosphoric acid, a molar ratio of the L-tyrosine to t