218272-04-9

Upstream product

• 218272-03-8 (4R,5R)-4-((S)-1-Azido-2-phenyl-ethyl)-5-((R)-1-azido-2-phenyl-ethyl)-2,2-dimethyl-[1,3]dioxolane 
• 50-70-4 D-sorbitol 
• 61849-47-6 1,2:5,6-Dianhydro-3,4-O-isopropylidene-D-sorbitol 
• 33493-69-5 (1R,1'R)-1,1'-[(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]diethane-1,2-diol 
• 218272-02-7 (R)-1-[(4R,5R)-5-((S)-1-Hydroxy-2-phenyl-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-2-phenyl-ethanol 

Relevant academic research and scientific papers

Stereoisomers of cyclic urea HIV-1 protease inhibitors: Synthesis and binding affinities

We have synthesized stereoisomers of cyclic urea HIV-1 protease inhibitors to study the effect of varying configurations on binding affinities. Four different synthetic approaches were used to prepare the desired cyclic urea stereoisomers. The original cy