218301-22-5

Basic information

• Product Name: 2-FLUORO-5-FORMYLBENZONITRILE
• Synonyms: 10014 2-FLUORO-5-FORMYL BENZONITRILE;6002 2-FLUORO-5-FORMYL BENZONITRILE;4-Fluoro-3-cyanobenzaldehyde;2-Fluoro-5-formylbenzonitrile 97%;2-Fluor-5-formylbenzonitrile;3-cyano-4-flluorobenzaldehyde;Benzonitrile, 2-fluoro-5-formyl-;CYANOFLUOROBENZALDEHYDE-3-4
• CAS NO: 218301-22-5
• Molecular Formula: C₈H₄FNO
• Molecular Weight: 149.12
• Product Categories: Aldehydes;Phenyls & Phenyl-Het;Benzaldehyde;Phenyls & Phenyl-Het;C8 to C9;Cyanides/Nitriles;Nitrogen Compounds;HALIDE;ALDEHYDE;Aromatic Nitriles
• Mol File: 218301-22-5.mol
• Article Data: 12

Chemical Properties

• Melting Point: 80-84 °C(lit.)
• Boiling Point: 215.603 °C at 760 mmHg
• Flash Point: 84.194 °C
• Appearance: /
• Density: 1.26 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Chloroform, Methanol
• CAS DataBase Reference: 2-FLUORO-5-FORMYLBENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-5-FORMYLBENZONITRILE(218301-22-5)
• EPA Substance Registry System: 2-FLUORO-5-FORMYLBENZONITRILE(218301-22-5)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 218301-22-5(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

Different sources of media describe the Uses of 218301-22-5 differently. You can refer to the following data:
1. 2-Fluoro-5-ForMyl-benzonitrile is used in the preparation of heterocyclic compounds as PARP inhibitors for medical use.
2. 2-Fluoro-5-formylbenzonitrile may be used in the synthesis of 3-cyano-4-fluorobenzyl bromide.

General Description

2-Fluoro-5-formylbenzonitrile is a benzonitrile derivative.

InChI:InChI=1S/C8H4FNO/c9-8-2-1-6(5-11)3-7(8)4-10/h1-3,5H

Upstream product

• 773095-28-6 5-(1,3-dioxolan-2-yl)-2-fluorobenzonitrile 
• 77771-02-9 3-bromo-4-fluorobenzaldehyde 
• 920-39-8 isopropylmagnesium bromide 
• 179897-89-3 5-Bromo-2-fluoro-benzonitrile 
• 218301-21-4 2-fluoro-5-bis-bromomethylbenzonitrile 
• 180302-35-6 5-bromomethyl-2-fluorobenzonitrile 
• 544-92-3 copper(I) cyanide 

Downstream Products

• 310424-28-3 (Z)-3-(3-Cyano-4-fluoro-phenyl)-acrylic acid methyl ester 
• 218301-23-6 C₁₁H₁₀FNO₂ 
• 648449-67-6 3-amino-benzo[d]isoxazole-5-carbaldehyde 
• 464191-88-6 5-Cyano-6-(3-cyano-4-fluorophenyl)-4-methyl-2-oxo-3,6-dihydro-2H-pyrimidine-1-carboxylic acid ethyl ester 
• 943732-53-4 tert-butyl 4-(3-cyano-4-fluorobenzyl)piperazine-1-carboxylate 
• 773095-28-6 5-(1,3-dioxolan-2-yl)-2-fluorobenzonitrile 
• 1193501-29-9 2-azido-5-formylbenzonitrile 
• 1193501-24-4 2-{4-(2-(4-azido-3-cyanophenyl)vinyl)-3-cyano-5,5-dimethyl-5H-furan-2-ylidene}malononitrile 
• 1259956-00-7 C₁₉H₁₃N₅O 
• 1196871-70-1 C₈H₄ClFN₂O 
• 1318072-98-8 ethyl 3-(3-cyano-4-fluorophenyl)-5-methylisoxazole-4-carboxylate 
• 1351989-64-4 2-Fluoro-5-(2,2,2-trifluoro-1-hydroxyethyl)benzonitrile 
• 1021298-68-9 2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzonitrile 
• 1620891-23-7 5-(2,3-dihydro-1H-perimidin-2-yl)-2-fluorobenzonitrile 

Relevant articles and documents

Novel indazole derivatives, and use thereof

The present invention refers to novel indazole derivatives, or pharmaceutically acceptable salts; and including DYRK1A DYRK1B active ingredient (Dual non-specificity tyrosine phosphorylation in a non-regulated kinase 1a) or a pharmaceutical composition for preventing or treating related disorders are disclosed. (by machine translation)

HETEROCYCLIC DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF

Disclosed are heterocyclic derivatives, methods for making them, compositions containing the same and uses thereof. Particularly, their pharmaceutical use as inhibitors of PARP is disclosed.

NOVEL OXADIAZOLE COMPOUNDS

Novel oxadiazole compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions as agonists or antagonists of the S1P family of G protein-coupled receptors for treating diseases associated with modulation o