21841-86-1Relevant academic research and scientific papers
Substituted 6-phenyl-3(2H)-pyridazinones useful as cardiotonic agents
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, (2008/06/13)
Substituted 6-phenyl-3(2H)-pyridazinone compounds are useful as cardiotonic agents. Said compounds cause a significant increase in myocardial contractility in the anesthetized dog. Said compounds are produced by reacting substituted γ-oxobenzenebutanoic acids with suitably substituted hydrazines to provide 6-phenyl-4,5-dihydro-3(2H)-pyridazinones which are dehydrogenated to the desired product. The intermediate 6-phenyl-4,5-dihydro-3(2H)-pyridazinones are themselves useful as cardiotonic agents.
VINYLATION OF 3-PYRIDAZONES
Shatalov, G.V.,Gridchin, S.A.,Mikhant'ev, B.I.
, p. 299 - 302 (2007/10/02)
The vinylation of 3-pyridazones through a step involving the production of 2-hydroxy- and 2-chloroethyl-substituted compounds with subsequent dehydrochlorination, as well as vinylation by means of vinyl acetate, in all cases leads only to N-vinyl derivati
