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218430-15-0

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218430-15-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 218430-15-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,8,4,3 and 0 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 218430-15:
(8*2)+(7*1)+(6*8)+(5*4)+(4*3)+(3*0)+(2*1)+(1*5)=110
110 % 10 = 0
So 218430-15-0 is a valid CAS Registry Number.

218430-15-0Upstream product

218430-15-0Downstream Products

218430-15-0Relevant articles and documents

Alpha 1a adrenergic receptor antagonists

-

, (2008/06/13)

This invention relates to certain novel compounds and derivatives thereof, their synthesis, and their use as alpha 1a adrenergic receptor antagonists. One application of these compounds is in the treatment of benign prostatic hyperplasia. These compounds are selective in their ability to relax smooth muscle tissue enriched in the alpha 1a receptor subtype without at the same time inducing hypotension. One such tissue is found surrounding the urethral lining. Therefore, one utility of the instant compounds is to provide acute relief to males suffering from benign prostatic hyperplasia, by permitting less hindered urine flow. Another utility of the instant compounds is provided by combination with a human 5-alpha reductase inhibitory compound, such that both acute and chronic relief from the effects of benign prostatic hyperplasia are achieved.

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