218439-26-0

Basic information

• Product Name: tert-Butyl-{(1S,2R)-2-(4-methoxy-benzyloxy)-1-[(S)-2-methyl-3-(2-methyl-[1,3]dithian-2-yl)-propyl]-3-vinyloxy-pent-4-enyloxy}-diphenyl-silane
• Synonyms: tert-Butyl-{(1S,2R)-2-(4-methoxy-benzyloxy)-1-[(S)-2-methyl-3-(2-methyl-[1,3]dithian-2-yl)-propyl]-3-vinyloxy-pent-4-enyloxy}-diphenyl-silane
• CAS NO: 218439-26-0
• Molecular Weight: 691.084
• Mol File: 218439-26-0.mol

Chemical Properties

• CAS DataBase Reference: tert-Butyl-{(1S,2R)-2-(4-methoxy-benzyloxy)-1-[(S)-2-methyl-3-(2-methyl-[1,3]dithian-2-yl)-propyl]-3-vinyloxy-pent-4-enyloxy}-diphenyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl-{(1S,2R)-2-(4-methoxy-benzyloxy)-1-[(S)-2-methyl-3-(2-methyl-[1,3]dithian-2-yl)-propyl]-3-vinyloxy-pent-4-enyloxy}-diphenyl-silane(218439-26-0)
• EPA Substance Registry System: tert-Butyl-{(1S,2R)-2-(4-methoxy-benzyloxy)-1-[(S)-2-methyl-3-(2-methyl-[1,3]dithian-2-yl)-propyl]-3-vinyloxy-pent-4-enyloxy}-diphenyl-silane(218439-26-0)

Safety Data

• Hazardous Substances Data: 218439-26-0(Hazardous Substances Data)

Upstream product

• 218439-44-2 (2S,3S,5S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxy)-5-methyl-6-(2-methyl-[1,3]dithian-2-yl)-hexanal 
• 218439-43-1 tert-Butyl-[(1S,3S)-1-[(R)-2-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-3-methyl-4-(2-methyl-[1,3]dithian-2-yl)-butoxy]-diphenyl-silane 
• 218439-24-8 (2R,3S,5S)-3-(tert-Butyl-diphenyl-silanyloxy)-2-(4-methoxy-benzyloxy)-5-methyl-6-(2-methyl-[1,3]dithian-2-yl)-hexan-1-ol 
• 218439-42-0 tert-Butyl-[(1S,3S)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-methyl-4-(2-methyl-[1,3]dithian-2-yl)-butoxy]-diphenyl-silane 
• 218439-16-8 (S)-4-Benzyl-3-[(2S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-butyryl]-oxazolidin-2-one 
• 218439-38-4 (S)-4-Benzyl-3-[(S)-4-(tert-butyl-dimethyl-silanyloxy)-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-butyryl]-oxazolidin-2-one 
• 218439-23-7 (2R,3S,5S)-3-(tert-Butyl-diphenyl-silanyloxy)-5-methyl-6-(2-methyl-[1,3]dithian-2-yl)-hexane-1,2-diol 
• 218439-39-5 Toluene-4-sulfonic acid (2S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-butyl ester 
• 218439-21-5 tert-Butyl-[(1S,3S)-1-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-methyl-4-(2-methyl-[1,3]dithian-2-yl)-butoxy]-dimethyl-silane 
• 218439-41-9 (1S,3S)-1-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-3-methyl-4-(2-methyl-[1,3]dithian-2-yl)-butan-1-ol 
• 218439-18-0 (2S,4S)-4-(tert-Butyl-dimethyl-silanyloxy)-4-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-butan-1-ol 
• 218439-40-8 tert-butyl((1S,3S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-iodo-3-methylbutoxy)dimethylsilane 
• 109-92-2 ethyl vinyl ether 
• 218439-25-9 (4R,5S,7S)-5-(tert-Butyl-diphenyl-silanyloxy)-4-(4-methoxy-benzyloxy)-7-methyl-8-(2-methyl-[1,3]dithian-2-yl)-oct-1-en-3-ol 

Downstream Products

• 218439-28-2 (E)-(6R,7S,9S)-7-(tert-Butyl-diphenyl-silanyloxy)-6-(4-methoxy-benzyloxy)-9-methyl-10-(2-methyl-[1,3]dithian-2-yl)-dec-4-enal 

Relevant articles and documents

Synthetic study on a 26-membered macrolide, amphidinolide B: Synthesis of the C1-C13 fragment

The C1-C13 fragment of amphidinolide B (1) was synthesized from D-erythrose (3). The Evans alkylation reaction protocol allowed the introduction of the stereogenic center at the CM position, which was unambiguously confirmed by a single X-ray crystallographic analysis.