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1-(3,4-difluorophenyl)-2-hydroxyethanone, commonly known as diflunisal, is a nonsteroidal anti-inflammatory drug (NSAID) characterized by its 1,2-diphenylethandione core and two fluorine atoms attached to the phenyl ring. 1-(3,4-difluorophenyl)-2-hydroxyethanone is recognized for its ability to alleviate pain and reduce inflammation, particularly in conditions like arthritis.

218449-33-3

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218449-33-3 Usage

Uses

Used in Pharmaceutical Industry:
1-(3,4-difluorophenyl)-2-hydroxyethanone is used as an anti-inflammatory agent for its ability to inhibit the production of prostaglandins, which play a key role in the regulation of inflammation, pain, and fever. Its efficacy in managing arthritis symptoms makes it a valuable addition to the pharmaceutical market.
Used in Pain Management:
As a pain-relieving medication, 1-(3,4-difluorophenyl)-2-hydroxyethanone is utilized to provide relief from various types of pain, including that associated with inflammation. Its NSAID classification allows it to be a common choice for patients seeking to manage their discomfort.
Used in Medical Treatments:
Diflunisal is also used in medical treatments where reducing inflammation and pain is necessary. Its oral tablet form and liver metabolism make it a convenient and accessible option for patients requiring such treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 218449-33-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,8,4,4 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 218449-33:
(8*2)+(7*1)+(6*8)+(5*4)+(4*4)+(3*9)+(2*3)+(1*3)=143
143 % 10 = 3
So 218449-33-3 is a valid CAS Registry Number.

218449-33-3Downstream Products

218449-33-3Relevant academic research and scientific papers

BENZOPYRAZOLE COMPOUND USED AS RHO KINASE INHIBITOR

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Paragraph 0233-0235; 0251-0253, (2021/02/25)

The invention relates to a benzopyrazole compound used as RHO kinase inhibitor, a pharmaceutical composition and uses thereof for preparing an RHO kinase inhibiting drug, and more specifically to said compound of formula (I-1), a pharmaceutically acceptable salt and isomer thereof.

DIHYDROOXADIAZINONES

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Page/Page column 227; 241; 242, (2019/02/15)

The present invention provides dihydrooxydiazinone compounds of general formula (I) : in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.

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