218457-71-7 Usage
General Description
BOC-D-3,4-DIMETHOXYPHENYLALANINE is a chemical compound that is commonly used in the field of biochemistry and pharmaceutical research. It is an amino acid derivative that features a BOC (tert-butoxycarbonyl) protecting group, and a 3,4-dimethoxyphenylalanine residue. BOC-D-3,4-DIMETHOXYPHENYLALANINE has been studied for its potential in developing new pharmaceutical drugs and has shown promising results in various research studies. BOC-D-3,4-DIMETHOXYPHENYLALANINE is typically used as a building block in the synthesis of peptide-based compounds, which makes it an important tool in the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 218457-71-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,8,4,5 and 7 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 218457-71:
(8*2)+(7*1)+(6*8)+(5*4)+(4*5)+(3*7)+(2*7)+(1*1)=147
147 % 10 = 7
So 218457-71-7 is a valid CAS Registry Number.
218457-71-7Relevant articles and documents
Discovery of pyrrolopyrimidine inhibitors of Akt
Blake, James F.,Kallan, Nicholas C.,Xiao, Dengming,Xu, Rui,Bencsik, Josef R.,Skelton, Nicholas J.,Spencer, Keith L.,Mitchell, Ian S.,Woessner, Richard D.,Gloor, Susan L.,Risom, Tyler,Gross, Stefan D.,Martinson, Matthew,Morales, Tony H.,Vigers, Guy P.A.,Brandhuber, Barbara J.
scheme or table, p. 5607 - 5612 (2010/11/17)
The discovery and optimization of a series of pyrrolopyrimidine based protein kinase B (Pkb/Akt) inhibitors discovered via HTS and structure based drug design is reported. The compounds demonstrate potent inhibition of all three Akt isoforms and knockdown of phospho-PRAS40 levels in LNCaP cells and tumor xenografts.
