218457-81-9 Usage
General Description
FMOC-D-3,4-DIMETHOXYPHENYLALANINE, also known as Fmoc-D-Dmp-OH, is a white to off-white crystalline chemical compound used notably within the field of scientific research. Its key properties are its tenacity to appear as solid dust with the molecular formula of C24H23NO5. This FMOC-protected amino acid derivative is commonly used in solid-phase peptide synthesis (SPPS) techniques, a process which aids in constructing peptides chains. It’s worth noting that it is generally stored at room temperature and should be handled with caution due to its irritant nature. As such, its main usage revolves around laboratory research purposes rather than household or commercial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 218457-81-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,8,4,5 and 7 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 218457-81:
(8*2)+(7*1)+(6*8)+(5*4)+(4*5)+(3*7)+(2*8)+(1*1)=149
149 % 10 = 9
So 218457-81-9 is a valid CAS Registry Number.
218457-81-9Relevant articles and documents
New synthetic amino acids for the design and synthesis of peptide-based metal ion sensors
Torrado, Alicia,Imperiali, Barbara
, p. 8940 - 8948 (2007/10/03)
The syntheses of two new nonstandard amino acids, Flu (6) and XBp (20), and a new synthesis of Dmd (12) are reported. These residues exhibit fluorescence, metal-coordination, and fluorescence-quenching properties, respectively. These building blocks have been incorporated into peptides via solid phase peptide synthesis to afford the prototype for a photoinduced electron transfer-based metal ion chemosensor. The fluorescence of the peptides is modulated upon metal binding. This results from a metal ion-induced conformational change that brings the side chains of the Flu and Dmd amino acids into proximity, thereby favoring photoinduced electron transfer (PET) fluorescence quenching.