218460-00-5

Basic information

• Product Name: (S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole
• Synonyms: (S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-2-oxazoline;(S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole;(S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-2-oxazoline 97%
• CAS NO: 218460-00-5
• Molecular Formula: C27H30NOP
• Molecular Weight: 415.51
• Mol File: 218460-00-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 134-138 °C
• Appearance: /
• Storage Temp.: ?20°C
• CAS DataBase Reference: (S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole(218460-00-5)
• EPA Substance Registry System: (S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole(218460-00-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 218460-00-5(Hazardous Substances Data)

Usage

Description

(S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole is a phosphine ligand characterized by a unique structure. It features a 4,5-dihydro-oxazole ring with a (S)-configuration and a tert-butyl group at the 4-position. The ligand also incorporates a bis(2-tolyl)phosphino group and a phenyl group attached to the oxazole ring. (S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole is distinguished by its chiral nature and is widely utilized in coordination chemistry.

Uses

Used in Coordination Chemistry:
(S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole is used as a chiral ligand in coordination chemistry for its ability to facilitate asymmetric catalysis in organic synthesis. Its distinctive structure and stereochemistry make it an essential component in the synthesis of enantiopure compounds, which are crucial for various chemical reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole is used as a key intermediate in the development of chiral drugs. Its ability to create enantiomerically pure compounds is vital for the synthesis of drugs with specific biological activities, ensuring the desired therapeutic effects and minimizing potential side effects.
Used in Chemical Synthesis:
(S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole is employed as a chiral ligand in chemical synthesis to produce enantiomerically pure compounds. Its unique structure allows for the creation of compounds with specific stereochemistry, which is essential for various applications, including the development of new materials, catalysts, and pharmaceuticals.
Used in Research and Development:
In research and development, (S)-2-[2-[Bis(2-tolyl)phosphino]phenyl]-4-tert-butyl-4,5-dihydro-oxazole is utilized as a chiral ligand to study the mechanisms of asymmetric catalysis and to develop new catalytic systems. Its unique properties make it a valuable tool for understanding the role of chirality in chemical reactions and for designing new enantioselective catalysts.