218595-22-3

Basic information

• Product Name: 7-Oxa-4-azaspiro[2.5]octane hydrochloride
• Synonyms: 7-Oxa-4-azaspiro[2.5]octane hydrochloride;7-oxa-4-azaspiro[2.5]octane hcl
• CAS NO: 218595-22-3
• Molecular Formula: C6H12ClNO
• Molecular Weight: 149.61858
• Mol File: 218595-22-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 7-Oxa-4-azaspiro[2.5]octane hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Oxa-4-azaspiro[2.5]octane hydrochloride(218595-22-3)
• EPA Substance Registry System: 7-Oxa-4-azaspiro[2.5]octane hydrochloride(218595-22-3)

Safety Data

• Hazardous Substances Data: 218595-22-3(Hazardous Substances Data)

Usage

Uses

7-Oxa-4-azaspiro[2.5]octane hydrochloride is used as a reactant in the preparation of aroylpiperazines as tachykinin antagonists.

Upstream product

• 218594-10-6 8-benzyl-5-oxa-8-azaspiro[2.5]octan-7-one 
• 218594-11-7 4-benzyl-7-oxa-4-azaspiro[2.5]octane 

Relevant articles and documents

AROYL-PIPERAZINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TACHYKININ ANTAGONISTS

This invention relates to piperazine derivatives of formula (I), wherein Y is bond or lower alkylene, R1 is aryl which may have substituent(s), R2 is aryl or indolyl, each of which may have substituent(s), R3 is hydrogen or lower alkyl, and R4 is as defined in the description, and its pharmaceutically acceptable salt, to processes for preparation thereof, to pharmaceutical composition comprising the same, and to a use of the same for treating or preventing Tachykinin-mediated diseases in human beings or animals. 1