218623-11-1

Basic information

• Product Name: 2-(5-methyl-2-nitro-benzyloxy)-tetrahydro-pyran
• Synonyms: 2-(5-methyl-2-nitro-benzyloxy)-tetrahydro-pyran
• CAS NO: 218623-11-1
• Molecular Weight: 251.282
• Mol File: 218623-11-1.mol

Chemical Properties

• CAS DataBase Reference: 2-(5-methyl-2-nitro-benzyloxy)-tetrahydro-pyran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-methyl-2-nitro-benzyloxy)-tetrahydro-pyran(218623-11-1)
• EPA Substance Registry System: 2-(5-methyl-2-nitro-benzyloxy)-tetrahydro-pyran(218623-11-1)

Safety Data

• Hazardous Substances Data: 218623-11-1(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 66424-92-8 5-methyl-2-nitrobenzyl alcohol 

Downstream Products

• 5858-28-6 5-methyl-2-nitrobenzaldehyde 
• 66424-92-8 5-methyl-2-nitrobenzyl alcohol 

Relevant articles and documents

Solvent free tetrahydropyranylation of alcohols and phenols over sulfuric acid adsorbed on silica gel

Alcohols and phenols are tetrahydropyranylated in the presence of sulfuric acid adsorbed on silica gel in high to excellent yields in solvent free conditions and is expedited by microwave irradiation. Addition of methanol performs the complete deprotection.

Sulphuric acid adsorbed on silica gel: An efficient catalyst for the protection and deprotection of alcohols with dihydropyran

Alcohols are tetrahydropyranylated in the presence of sulphuric acid adsorbed on silica gel in dichloromethane in good to excellent yields. Addition of methanol brings about the complete deprotection.