21864-67-5

Usage

Uses

Used in Organic Synthesis:
2,6-Dimethoxybenzamide is utilized as a building block in the synthesis of a wide range of pharmaceuticals and agrochemicals. Its structural features make it a valuable component in the creation of diverse chemical entities, contributing to the development of new drugs and agricultural products.
Used in Dye Synthesis:
In the dye industry, 2,6-Dimethoxybenzamide serves as an intermediate for the synthesis of various dyes. Its chemical properties allow for the production of dyes with specific color characteristics and stability, which are essential for different applications such as textiles, printing, and other industrial uses.
Used in Lubricant Production:
2,6-Dimethoxybenzamide is also employed in the formulation of lubricants. Its inclusion in lubricant compositions can enhance their performance, potentially improving the efficiency and longevity of machinery and equipment that rely on these lubricants.
Used in UV Stabilizer Synthesis:
2,6-Dimethoxybenzamide is used as an intermediate in the synthesis of UV stabilizers, which are crucial in protecting materials from the degrading effects of ultraviolet radiation. This application is particularly relevant in the plastics and coatings industries, where UV resistance is a key property.
Used in Pharmaceutical Research:
2,6-Dimethoxybenzamide has been studied for its potential pharmacological properties, such as anti-inflammatory and analgesic activities. Its exploration in this field indicates a promising avenue for the development of new therapeutic agents.
However, it is important to note that the toxicological properties and environmental impact of 2,6-Dimethoxybenzamide have not been extensively researched, which may be a consideration for future applications and development.

Upstream product

• 1989-53-3 2,6-dimethoxybenzoyl chloride 
• 16932-49-3 2,6-dimethoxybenzonitrile 
• 7664-93-9 sulfuric acid 
• 82558-50-7 isoxaben 

Downstream Products

• 906126-81-6 (E)-2,6-dimethoxy-N-3-phenylacryloylbenzamide 
• 906126-89-4 (3R)-N-(4,4-dicyano-3-phenylbutyryl)-2,6-dimethoxybenzamide 
• 4340-40-3 2,6-Dimethoxybenzoyl isocyanate 

Relevant academic research and scientific papers

Electrochemical C-H cyanation of electron-rich (Hetero)arenes

A straightforward method for the electrochemical C-H cyanation of arenes and heteroarenes that proceeds at room temperature in MeOH, with NaCN as the reagent in a simple, open, undivided electrochemical cell is reported. The platinum electrodes are passivated by ad-sorbed cyanide, which allows conversion of an exceptionally broad range of electron-rich substrates all the way down to dialkyl arenes. The cyanide electrolyte can be replenished with HCN, opening opportunities for salt-free industrial C-H cyanation.

UNEXPECTED HYDROLYSIS OF 5-AMINOISOXAZOLBENZOYLAMIDE HERBICIDE ISOXABEN INTO 5-ISOXAZOLINONE

The benzoylamide derivative of 5-aminoisoxazol, i.e. the herbicide isoxaben 1 (N--2,6-dimethoxybenzamide) was transformed by aqueous acid hydrolysis into the unexpected 5-isoxazolinone 3 (3-(1-ethyl-1-methylpropyl)isoxazolin 5-one) plus mainly 2,6-dimethoxybenzamide 4.The expected 5-aminoisoxazol 7 (5-amino-3-(1-ethyl-1-methylpropyl)isoxazol) was not generated, except in very low amounts when high acid concentrations were used.In separate hydrolysis trials made in similar aqueous acid conditions, it was observed that the 5-aminoisoxazol 7 and 5-isoxazolinone 3 were not transformed.The 5-isoxazolinone 3 formed by isoxaben 1 acid hydrolysis thus was the first generated product, and was not formed by the consecutive nucleophilic substitution of 5-aminoisoxazol 7 which would have been formed in a first step.This unexpected 5-amino C-N bond cleavage by nucleophilic attack of H2O at the 5-C of the isoxazol ring of isoxaben 1 -instead of the usual amide CO-N bond cleavage- probably is due to the positive charge existing at the 5-C atom of the isoxazol ring.The acid hydrolysis pathway observed for isoxaben 1 also is the main soil metabolism pathway.The absence of formation of an aromatic amino compound by chemical hydrolysis reduces the concern as to their potential transformation into carcinogenic nitroso or azo compounds in soil.On the other hand, isoxaben 1 was not hydrolyzed in aqueous dilute alkali.