21865-10-1Relevant academic research and scientific papers
A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent
Anselmi, Silvia,Liu, Siyu,Kim, Seong-Heun,Barry, Sarah M.,Moody, Thomas S.,Castagnolo, Daniele
supporting information, p. 156 - 161 (2021/01/14)
A mild, chemoselective and sustainable biocatalysed synthesis of sulfoxides has been developed exploiting CALB and using AcOEt with a dual role of more environmentally friendly reaction solvent and enzyme substrate. A series of sulfoxides, including the drug omeprazole, have been synthesised in high yields and with excellent E-factors.
Efficient aerobic oxidation of phosphines, phosphites, and sulfides by using trialkylborane
Motoshima, Kosuke,Sato, Akinori,Yorimitsu, Hideki,Oshima, Koichiro
experimental part, p. 2229 - 2231 (2009/08/08)
Treatment of phosphines, phosphites, or sulfides with trialkylborane under air afforded the corresponding oxides in good yields.
