21873-50-7 Usage
Uses
Used in Pharmaceutical Industry:
6-FLUORO-4-HYDROXYQUINOLINE is used as an intermediate in the synthesis of various pharmaceuticals for its versatile reactivity and unique structure, contributing to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
6-FLUORO-4-HYDROXYQUINOLINE is used as an intermediate in the synthesis of agrochemicals, providing a foundation for the development of new pesticides and other agricultural chemicals with enhanced efficacy and selectivity.
Used in Antimicrobial Applications:
6-FLUORO-4-HYDROXYQUINOLINE is studied for its potential antimicrobial properties, making it a promising candidate for the development of new antimicrobial agents to combat drug-resistant bacteria and other microbial infections.
Used in Antiviral Applications:
6-FLUORO-4-HYDROXYQUINOLINE has been studied for its potential antiviral properties, indicating its potential use in the development of new antiviral drugs to treat viral infections and mitigate the impact of emerging viral diseases.
Used in Organic Synthesis:
6-FLUORO-4-HYDROXYQUINOLINE serves as a versatile building block in organic synthesis, enabling the creation of a wide range of chemical compounds with diverse applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 21873-50-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,8,7 and 3 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 21873-50:
(7*2)+(6*1)+(5*8)+(4*7)+(3*3)+(2*5)+(1*0)=107
107 % 10 = 7
So 21873-50-7 is a valid CAS Registry Number.
21873-50-7Relevant academic research and scientific papers
Direct C-3-alkenylation of quinolones via palladium-catalyzed C-H functionalization
Li, Mingzong,Li, Liangxi,Ge, Haibo
supporting information; experimental part, p. 2445 - 2449 (2010/12/25)
An unprecedented C-3-alkenylation of quinolones was reported through palladium-catalyzed C-H functionalization with 1% catalyst loading. This method provides an efficient route to a variety of new quinolone derivatives.
Microwave-assisted synthesis of fluoroquinolones and their nucleosides as inhibitors of HIV integrase
Adams, Martina M.,Bats, Jan W.,Nikolaus, Nadja V.,Witvrouw, Myriam,Debyser, Zeger,Engels, Joachim W.
, p. 978 - 990 (2008/09/18)
Six fluoroquinolone ribonucleosides were synthesized by using microwave irradiation starting from fluoroanilines. In most cases the microwave application proved superior in time and yield, especially the one step decarboxylation of the carboxyquinolone esters 3a-3c and the Vorbrueggen glycosylation. The former led to the new type of fluoroquinolone ribosides 8a-8c. Compound 8c in the crystal structure showed C3′-endo and anti conformation. The nucleosides were examined, but found inactive against the replication of HIV-1(IIIB) in cell culture, while they were toxic for the cells at a 50% cytotoxic concentration ranging from 31 to >125 μg/ml. But measurements of the inhibitory effects against HIV-1 integrase enzymatic activity showed an interesting activity for compound 8c.
AMINOCYCLOHEXENE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY
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Page/Page column 41, (2010/02/06)
Cyclohexene derivatives and pharmaceutically acceptable derivatives thereof useful in methods of treatment of bacterial infections in mammals, particularly man.
