218774-06-2Relevant academic research and scientific papers
Design and synthesis of dipeptidyl α',β'-epoxy ketones, potent irreversible inhibitors of the cysteine protease cruzain
Roush, William R.,Gonzalez, Florenci V.,McKerrow, James H.,Hansell, Elizabeth
, p. 2809 - 2812 (2007/10/03)
The dipeptidyl epoxy ketone 4 is a potent, irreversible inhibitor of cruzain, a cysteine protease isolated from Trypanosoma cruzi, with an apparent second order inhibition rate constant of 330,000 sec-1 M-1.
