218792-63-3Relevant academic research and scientific papers
Exploration of β-turn scaffolding motifs as components of sialyl Le(x) mimetics and their relevance to P-selectin
Hanessian, Stephen,Huynh, Hoan K.,Reddy, Gurijala V.,McNaughton-Smith, Grant,Ernst, Beat,Kolb, Hartmuth C.,Magnani, John,Sweeley, Charla
, p. 2803 - 2808 (2007/10/03)
Monocyclic and bicyclic lactam units representing β-turn surrogate were incorporated into a sialyl Le(x) structure by replacement of the natural sugar components. Low micromolar activity was found in a new P-selectin binding assay.
