218897-93-9

Upstream product

• 951-98-4 2-Oxo-propionic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 

Downstream Products

• 218897-96-2 1,2,3,4,5,6-Hexahydro-azepino[4,5-b]indole-5-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 218897-95-1 1,2,3,6-Tetrahydro-azepino[4,5-b]indole-5-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 218897-94-0 1-Bromomethyl-2,3,4,9-tetrahydro-1H-β-carboline-1-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 

Relevant academic research and scientific papers

Synthesis of vinca alkaloids and related compounds, LXXXVII. Reversed enantioselectivity in different approaches

Using the same chiral auxiliaries during the enantioselective synthesis of vincamine the absolute configuration depends on the selected approach.Starting from Wenkert enamine the natural (+)-vincamine, while using the reaction sequence through vincadiffor