218898-51-2Relevant academic research and scientific papers
The Nazarov cyclization of β-carbonyl-β′-furyl-divinyl ketones and related compounds as induced by perchloric acid
Fernández Mateos,Martín De La Nava,Rubio González
, p. 1049 - 1057 (2001)
Diluted solutions of perchloric acid and acetic anhydride are introduced as a new catalyst for cationic cyclizations. The influence of the strong acid concentration and the nature of the anhydride have been studied in four types of Nazarov substrates.
Synthesis of C-seco Limonoid Model Insect Antifeedants Related to Ochinolide
Mateos, A. Fernandez,Nava, E. Martin de la,Coca, G. Pascual,Silvo, A. Ramos,Gonzales, R. Rubio
, p. 1372 - 1374 (2007/10/03)
A short and selective synthesis of C-seco limonoid model insect antifeedant related to ocinolide was accomplished in seven steps from α-cyclocitral.The key steps are the electrocyclization of a β-acyl divinyl ketone induced by perchloric acid, and a selective retroclaisen reaction.A rare example of atropisomerism was found in the trisubstituted cyclopentenone 6 key intermediate.
