21890-09-5

Usage

Uses

Used in Pharmaceutical Industry:
2-methyl-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-1H-cyclopenta[12]annulene is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable component in the creation of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-methyl-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-1H-cyclopenta[12]annulene is employed as a precursor in the synthesis of agrochemicals. Its versatile chemical properties allow for the development of new pesticides, herbicides, and other agricultural chemicals that can improve crop protection and yield.
Used in Material Science Industry:
2-methyl-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-1H-cyclopenta[12]annulene is utilized as a key component in the development of advanced materials in material science. Its potential for functionalization contributes to the creation of new polymers, coatings, and other materials with enhanced properties for various applications.
It is important to handle 2-methyl-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-1H-cyclopenta[12]annulene with care due to its flammability and potential health hazards. Proper safety measures should be followed when working with 2-methyl-2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-1H-cyclopenta[12]annulene to ensure the safety of individuals and the environment.

Upstream product

• 830-13-7 cyclododecanone 
• 62599-49-9 2-(2'-methylprop-2'-enyl)cyclododecan-1-one 
• 77146-09-9 4,5,6,7,8,9,10,11,12,13-decahydro-2-methyl-1H-cyclopentacyclododecene 
• 80468-66-2 14-methyl-13-phenylsulfonylbicyclo<10.3.0>pentadec-1(12)-ene 

Downstream Products

• 956-82-1 3-methylcyclopentadecanone 
• 36399-15-2 3-methyl-4⁽⁵⁾-cyclopentadecen-1-one 
• 63314-79-4 3-methyl-5-cyclopentadecen-1-one 
• 21890-10-8 3-methylcyclopentadecane-1,5-dione 

Relevant academic research and scientific papers

Ketone, particularly a method for preparing a large cyclic ketone

Ketones of the formula II where A is optionally alkyl-substituted C2-C12-alkanediyl, R1 and R2 are each, independently of one another, C1-C6-alkyl, or R1 and R2 together form optionally alkyl-substituted C3-C10-alkanediyl, and R3 is hydrogen or C1-C6-alkyl, are prepared by reacting a cyclic olefin of the formula I with dinitrogen monoxide to form the ketone of the formula II. The ketone of the formula II can be further hydrogenated to form the saturated ketone of the formula III. Macrocyclic ketones of the formula III, e.g. muscone, are sought after as fragrances.

PROCESS FOR PREPARING KETONES, IN PARTICULAR MACROCYCLIC KETONES

Ketones of the formula II where A is optionally alkyl-substituted C2-C12-alkanediyl, R1 and R2 are each, independently of one another, C1-C6-alkyl, or R1 and R2 together form optionally alkyl-substituted C3-C10-alkanediyl, and R3 is hydrogen or C1-C6-alkyl, are prepared by reacting a cyclic olefin of the formula I with dinitrogen monoxide to form the ketone of the formula II. The ketone of the formula II can be further hydrogenated to form the saturated ketone of the formula III. Macrocyclic ketones of the formula III, e.g. muscone, are sought after as fragrances.

Macrocyclic carbonyl compounds, process for their preparation and their use as starting materials for the preparation of bicyclic unsaturated hydrocarbons

Compounds of formula STR1 having a double bond in one of the positions indicated by the dotted lines and wherein R represents a hydrogen atom or a methyl radical are utilized as starting materials for the preparation of bicyclic unsaturated hydrocarbons of formula STR2 (R=H, CH3). Conversion of (II) to (I) occurs via thermal treatment in the presence of a metal catalyst. Disclosed is also a process for the preparation of (II).

A Novel Pentaannulation Sequence. Facile Access to Key Intermediates for the Synthesis of ExaltoneR and Muscone

Treatment of the sulfonyl ketones 1 a and 1 b with potassium t-butoxide in toluene or with potassium hydroxyde in toluene/dimethyl sulfoxide affords in high yield the bicyclic dienes 3 a and 3 b, importantbprecursors for exaltoneR and (+/-)-muscone.An Application of this novell pentaannulation sequence is demonstrated for the solfonyl ketones 6, 10, and 14.An intermolecular variant is exemplified by the synthesis of diene 22.

Process for preparing unsaturated bicyclic hydrocarbons

New process for preparing unsaturated bicyclic hydrocarbons useful as intermediate compounds in the preparation of macrocyclic ketones.

Polyunsaturated bicyclic compounds, their preparation and use of same as starting materials for preparing monounsaturated bicyclic compounds

New polyunsaturated compounds, their preparation and their use as starting materials for preparing monounsaturated bicyclic compounds useful as intermediates in the preparation of macrocyclic ketones.