218917-26-1Relevant academic research and scientific papers
Synthesis of 1,2-O-isopropylidene-3,5-O-propylidene-α-D-glucofuranose as a convenient precursor of both 6-O-alkyl and 6-O-glycidyl-D-glucose amphiphiles
Vanbaelinghem, Laurence,Gode, Paul,Goethals, Gerard,Martin, Patrick,Ronco, Gino,Villa, Pierre
, p. 89 - 94 (1998)
1,2-O-Isopropylidene-3,5-O-propylidene-α-D-glucofuranose (3) was synthesized by conversion of 3-O-allyl-1,2-O-isopropylidene-α-D-glucofuranose (1) into its 3-O-prop-1-enyl isomer (2), followed by rapid acid-catalysed intramolecular acetalation in an aprotic solvent. The diacetal 3 was used as the precursor of 6-O-alkyl and 6-O-glucidyl-D-glucose amphiphiles, which show thermotropic and lyotropic liquid-crystalline properties. Copyright (C) 1997 Elsevier Science Ltd.
