21893-97-0Relevant academic research and scientific papers
Photoinduced DNA Interstrand Cross-Linking by Benzene Derivatives: Leaving Groups Determine the Efficiency of the Cross-Linker
Fan, Heli,Peng, Xiaohua
, p. 493 - 506 (2020/12/22)
We have synthesized and characterized two small libraries of 2-OMe or 2-NO2-benzene analogues 2a-i and 3a-i containing a wide variety of leaving groups. Irradiation of these compounds at 350 nm generated benzyl radicals that were spontaneously oxidized to
SOD activity and DNA binding properties of a new symmetric porphyrin Schiff base ligand and its metal complexes
?ay, Sevim,K?se, Muhammet,Tümer, Ferhan,G?lcü, Ay?egül,Tümer, Mehmet
, p. 821 - 838 (2015/07/20)
4-Methoxy-2,6-bis(hydroxymethyl)phenol (1) was prepared from the reaction of 4-methoxyphenol and formaldehyde. The compound (1) was then oxidized to the 4-methoxy-2,6-diformylphenol (2) compound. Molecular structure of compound (2) was determined by X-ray
Coordination cluster analogues of the high-Spin [Mn19] system with functionalized 2,6-Bis(hydroxymethyl)phenol ligands
Mameri, Samir,Ako, Ayuk M.,Yesil, Fatma,Hibert, Marcel,Lan, Yanhua,Anson, Christopher E.,Powell, Annie K.
, p. 4326 - 4334 (2015/03/30)
A series of 2,6-bis(hydroxymethyl)-4-R-phenol ligands (H3LR; R = H, F, Cl, Br, I, Ph, NH2, NO2, SMe) have either been newly synthesized or the existing syntheses have been significantly improved to investigate ligand-functionalized analogues of the previously published coordination cluster [MnIII12MnII7(μ4-O)8(μ3-N3)8(HLMe)12(MeCN)6]Cl2·10MeOH·MeCN (1) with S = 83/2. The crystal structures and magnetic properties of three such Mn19 clusters, namely, [MnIII12MnII7(μ4-O)8(HLH)12(μ3-Cl)7(μ3-OMe)(MeOH)6]Cl2·16H2O·10MeOH·MeCN (3), [MnIII12MnII7(μ4-O)8(HLI)12(μ3-N3)8(MeOH)6](O2CH)2·16MeOH·10MeCN (4) and [MnIII12MnII7(μ4-O)8(μ3-Cl)7.7(μ3-OMe)0.3(HLSMe)12(MeOH)6]Cl2·27MeOH (5) are reported and compared to those of the parent cluster. When these ligands are functionalized with substituents of moderate electronegativity, it is possible to synthesize Mn19 analogues; however, when such ligands bear highly electron-donating (amino) or -withdrawing (nitro) substituents, the Mn19 analogues are no longer accessible. The Mn19 cluster framework is both magnetically and structurally robust with respect to the electron-donor/acceptor characteristics of the ligand substituent; therefore, the Mn19 system is an excellent platform for peripheral chemical engineering. The robustness of the inorganic {MnIII12MnII7(μ4-O)8} core of Mn19 systems with variously functionalized encapsulating ligands is demonstrated by the invariance of the record S = 83/2 spin state. Chemical modification aimed towards attaching the molecule to various substrates does not interfere with the electronic structure.
Studies on the total synthesis of lactonamycin: Synthesis of the fused pentacyclic B-F ring unit
Jacques, Sylvain A.,Michaelis, Simon,Gebhardt, Bjoern,Blum, Andreas,Lebrasseur, Nathalie,Larrosa, Igor,White, Andrew J. P.,Barrett, Anthony G. M.
experimental part, p. 107 - 113 (2012/01/15)
This paper describes an approach towards the total synthesis of lactonamycin with the elaboration of a key pentacyclic unit. Key steps include the synthesis of benzyl bromide 8 in eight steps and 23 % overall yield starting from 4-methoxyphenol; a high-yi
UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS
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, (2010/05/13)
Benzotriazole UV/Visible light-absorbing monomers are disclosed. The UV/Vis absorbers are particularly suitable for use in intraocular lens materials.
UV/VISIBLE LIGHT ABSORBERS FOR OPHTHALMIC LENS MATERIALS
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Page/Page column 11, (2010/06/11)
Benzotriazole UV/Visible light-absorbing monomers are disclosed. The UV/Vis absorbers are particularly suitable for use in intraocular lens materials.
Studies on the total synthesis of lactonamycin: Synthesis of the CDEF ring system
Wehlan, Hermut,Jezek, Eva,Lebrasseur, Nathalie,Pave, Gregoire,Roulland, Emmanuel,White, Andrew J. P.,Burrows, Jeremy N.,Barrett, Anthony G. M.
, p. 8151 - 8158 (2007/10/03)
A concise and efficient synthesis of the tetracyclic CDEF ring system of lactonamycin (1) is described. The key step involved the Lewis acid mediated, intramolecular Friedel-Crafts acylation of carboxylic acid 6 to produce the tetracyclic CDEF core struct
Towards a total synthesis of the new anticancer agent mensacarcin: Synthesis of the carbocyclic core
Tietze, Lutz F.,Stewart, Scott G.,Polomska, Marta E.,Modi, Andrea,Zeeck, Axel
, p. 5233 - 5242 (2007/10/03)
A synthesis of the carbocyclic core associated with the new anti-cancer agent mensacarcin (1) is reported. The strategy involves the synthesis of several novel highly substituted aromatic compounds, such as 12 and 23. The lithium derivative of 12 readily
Dinuclear zinc(II)-iron(III) and iron(II)-iron(III) complexes as models for purple acid phosphatases
Albedyhl, Sabine,Averbuch-Pouchot, Marie Therese,Belle, Catherine,Krebs, Bernt,Pierre, Jean Louis,Saint-Aman, Eric,Torelli, Stephane
, p. 1457 - 1464 (2007/10/03)
The heterodinuclear ZnIIFeIII complex 1 and the isostructural FeIIFeIII complex 2 with the dinucleating ligand from 2,6-bis[{bis(2-pyridylmethyl)amino}methyl]-4-methoxyphenol (HBPMOP, 3) were prepared and charac
