21905-71-5

Usage

Molecular Structure

2-(2-Methylphenoxy)benzoic acid methyl ester consists of a benzene ring attached to a benzoic acid group, with an additional methyl ester group attached to the acid.

Usage

Commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds.

Potential Applications

Has potential applications in the field of medicine and agriculture due to its ability to act as a building block for the synthesis of various biologically active compounds.

Other Uses

May have other uses in the field of materials science and academic research.

Upstream product

• 610-97-9 o-iodo-methyl-benzoic acid 
• 95-48-7 ortho-cresol 
• 610-94-6 2-bromobenzoic acid methyl ester 

Downstream Products

• 617-01-6 o-tolyl 2-hydroxybenzoate 

Relevant academic research and scientific papers

A photoredox-neutral Smiles rearrangement of 2-aryloxybenzoic acids

We report on the use of visible light photoredox catalysis for the radical Smiles rearrangement of 2-aryloxybenzoic acids to obtain aryl salicylates. The method is free of noble metals and operationally simple and the reaction can be run under mild batch or flow conditions. Being a redox neutral process, no stoichiometric oxidants or reductants are needed.

Synthesis of diaryl ethers using an easy-to-prepare, air-stable, soluble copper(I) catalyst

We have found that bromo(triphenylphosphine)copper(I), an air-stable and soluble copper(I) complex, can be used as a catalyst in the synthesis of diaryl ethers. Using this catalyst, we have synthesized diaryl ethers from electron-rich aryl bromides and electron-rich phenols in the presence of cesium carbonate, in 17-24 h, in NMP. We also found that electron-deficient aryl bromides couple with phenols in the presence of cesium carbonate, in 6 h in NMP at 70°C, without the catalyst.