219138-06-4

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Basic information

Product Name: Z-VEID-AFC
Synonyms: MCA-VDQVDGWK(DNP)-NH2;MCA-VQVDGW-K(DNP)-NH2;MCA-VAL-ASP-GLN-VAL-ASP-GLY-TRP-LYS(DNP)-NH2;MCA-VAL-GLN-VAL-ASP-GLY-TRP-LYS(DNP)-NH2;CASPASE-6 SUBSTRATE III, FLUOROGENIC;CASPASE 6 (MCH2) SUBSTRATE 2, FLUOROGENIC;CASPASE-6, SUBSTRATE, FLUOROGENIC;CASPASE-7 SUBSTRATE I, FLUOROGENIC
CAS NO:219138-06-4
Molecular Formula: C38H44F3N5O12
Molecular Weight: 819.78
EINECS: N/A
Product Categories: peptide;Pepetides
Mol File: 219138-06-4.mol
Article Data: 0

Chemical Properties

Melting Point: N/A
Boiling Point: 1087.7±65.0 °C(Predicted)
Flash Point: N/A
Appearance: /powder
Density: 1.380±0.06 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: −20°C
Solubility: DMSO/DMF: 20 mM
PKA: 4.09±0.10(Predicted)
Water Solubility: DMSO/DMF: 20 mM
CAS DataBase Reference: Z-VEID-AFC(CAS DataBase Reference)
NIST Chemistry Reference: Z-VEID-AFC(219138-06-4)
EPA Substance Registry System: Z-VEID-AFC(219138-06-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany: 3
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 219138-06-4(Hazardous Substances Data)

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219138-06-4 Usage

General Description

Z-VEID-AFC is a synthetic chemical compound that is commonly used as a substrate for caspase-6, a protein involved in programmed cell death, or apoptosis, and inflammation. Z-VEID-AFC is often utilized in research and drug development to study the mechanisms of cell death and its potential for therapeutic targeting. Z-VEID-AFC is a fluorogenic substrate, meaning it produces a fluorescent signal upon cleavage by caspase-6, allowing for the convenient and sensitive measurement of caspase-6 activity in biological samples. Its use provides valuable insights into the role of caspase-6 in various disease processes and facilitates the screening and development of potential anti-inflammatory and anti-cancer drugs.

Check Digit Verification of cas no

The CAS Registry Mumber 219138-06-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,1,3 and 8 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 219138-06:
(8*2)+(7*1)+(6*9)+(5*1)+(4*3)+(3*8)+(2*0)+(1*6)=124
124 % 10 = 4
So 219138-06-4 is a valid CAS Registry Number.

219138-06-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name	Z-VEID-AFC

1.2 Other means of identification

Product number	-
Other names	PASE-6,SUBSTRATE,FLUOROGENIC

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:219138-06-4 SDS

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