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Z-VEID-AFC is a synthetic chemical compound that serves as a substrate for caspase-6, a protein that plays a crucial role in programmed cell death (apoptosis) and inflammation. As a fluorogenic substrate, Z-VEID-AFC produces a fluorescent signal upon cleavage by caspase-6, enabling the sensitive and convenient measurement of caspase-6 activity in biological samples. This property makes Z-VEID-AFC a valuable tool in research and drug development for studying the mechanisms of cell death and its potential for therapeutic targeting.

219138-06-4

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219138-06-4 Usage

Uses

Used in Research and Drug Development:
Z-VEID-AFC is used as a research tool for studying the mechanisms of cell death and inflammation, as well as for the development of potential anti-inflammatory and anti-cancer drugs. Its ability to produce a fluorescent signal upon cleavage by caspase-6 allows for the convenient and sensitive measurement of caspase-6 activity, providing valuable insights into the role of caspase-6 in various disease processes.
Used in Pharmaceutical Industry:
Z-VEID-AFC is used as a substrate for the development of drugs targeting caspase-6 activity. By facilitating the measurement of caspase-6 activity, Z-VEID-AFC aids in the screening and development of potential therapeutic agents that can modulate caspase-6 function, potentially leading to the discovery of new treatments for diseases associated with abnormal cell death and inflammation.
Used in Diagnostic Applications:
Z-VEID-AFC can be employed as a diagnostic tool for assessing caspase-6 activity in biological samples. Its ability to produce a fluorescent signal upon cleavage by caspase-6 makes it a sensitive and convenient method for detecting and monitoring caspase-6 activity in various disease states, potentially aiding in the diagnosis and prognosis of conditions related to abnormal cell death and inflammation.

Check Digit Verification of cas no

The CAS Registry Mumber 219138-06-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,1,3 and 8 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 219138-06:
(8*2)+(7*1)+(6*9)+(5*1)+(4*3)+(3*8)+(2*0)+(1*6)=124
124 % 10 = 4
So 219138-06-4 is a valid CAS Registry Number.

219138-06-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Z-VEID-AFC

1.2 Other means of identification

Product number -
Other names PASE-6,SUBSTRATE,FLUOROGENIC

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:219138-06-4 SDS

219138-06-4Upstream product

219138-06-4Downstream Products

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