219138-21-3

Basic information

• Product Name: AC-IETD-PNA
• Synonyms: AC-ILE-GLU-THR-ASP-PNA;ACETYL-L-ISOLEUCYL-L-GLUTAMYL-L-THREONYL-L-ASPARTIC ACID ALPHA-(4-METHYLCOUMARYL-7-AMIDE);Z-ALA-ALA-ASP-AFC;N-ACETYL-ILE-GLU-THR-ASP P-NITROANILIDE;N-ACETYL-ILE-GLU-THR-ASP-P-NITROANILIDE PNA;N-ACETYL-ILE-GLU-THR-ASP-7-AMIDO-4-METHYLCOUMARIN;N-ACETYL-ILE-GLU-THR-ASP-7-AMINO-4-METHYLCOUMARIN AMC;AC-ILE-GLU-THR-ASP-P-NITROANILIDE
• CAS NO: 219138-21-3
• Molecular Formula: C27H38N6O12
• Molecular Weight: 638.62
• Product Categories: Peptide;Pepetides
• Mol File: 219138-21-3.mol
• Article Data: 0

Chemical Properties

• Appearance: white/powder
• Storage Temp.: −20°C
• Solubility: DMSO/DMF: 1 mg/mL
• CAS DataBase Reference: AC-IETD-PNA(CAS DataBase Reference)
• NIST Chemistry Reference: AC-IETD-PNA(219138-21-3)
• EPA Substance Registry System: AC-IETD-PNA(219138-21-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 219138-21-3(Hazardous Substances Data)

Usage

General Description

AC-IETD-PNA, also known as Caspase-8 Substrate, is a chemical compound often used in scientific research, specifically in the study of apoptosis or programmed cell death. AC-IETD-PNA functions as a crucial substrate for caspase-8, an enzyme that plays a vital role in the initiation of apoptosis. Therefore, AC-IETD-PNA is important for understanding cellular processes and potentially developing treatments for diseases such as cancer, where the regulation of cell death is disrupted.