Z-HIS(BZL)-OH, also known as Benzyloxycarbonyl-L-histidine, is a chemical compound that belongs to the family of amino acids and peptides. It is primarily used for research purposes and is a fundamental component of cells that carry out critical functions in the body. With a molecular formula of C14H14N4O4, Z-HIS(BZL)-OH is derived from L-Histidine and is utilized in the production of various pharmaceuticals and medicinal research processes due to its important biological activity. The benzyloxycarbonyl group (Bzl or Z) acts as a protective group, enhancing the effectiveness and optimization of synthesized drugs. However, caution must be exercised when handling Z-HIS(BZL)-OH due to its potential hazards and reactivity.
21929-66-8
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Basic information
- Product Name: Z-HIS(BZL)-OH
- Synonyms: Z-N-IM-BENZYL-L-HISTIDINE;Z-HIS(BZL)-OH;Z-HISTIDINE(BZL)-OH;N-CARBOBENZOXY-IM-BENZYL-L-HISTIDINE;NALPHA-CBZ-N-IM-BENZYL-L-HISTIDINE;N-ALPHA-CARBOBENZOXY-N-IM-BENZYL-L-HISTIDINE;N-Benzyloxycarbonyl-im-benzyl-L-histidine;Cbz-His(Bzl)-OH
- CAS NO:21929-66-8
- Molecular Formula: C21H21N3O4
- Molecular Weight: 379.41
- EINECS: N/A
- Product Categories: Cbz-Amino acid series
- Mol File: 21929-66-8.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 649.3°Cat760mmHg
- Flash Point: 346.5°C
- Appearance: /
- Density: 1.25g/cm3
- Vapor Pressure: 9.61E-18mmHg at 25°C
- Refractive Index: 1.613
- Storage Temp.: −20°C
- Solubility: N/A
- BRN: 55593
- CAS DataBase Reference: Z-HIS(BZL)-OH(CAS DataBase Reference)
- NIST Chemistry Reference: Z-HIS(BZL)-OH(21929-66-8)
- EPA Substance Registry System: Z-HIS(BZL)-OH(21929-66-8)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 21929-66-8(Hazardous Substances Data)
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21929-66-8 Usage
Uses
Used in Pharmaceutical Industry:Z-HIS(BZL)-OH is used as a key intermediate compound for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its important biological activity makes it a valuable component in the creation of medications that target specific health conditions.
Used in Medicinal Research:
Z-HIS(BZL)-OH is used as a research tool in the field of medicinal chemistry, allowing scientists to study the interactions and mechanisms of action of different drug candidates. This helps in understanding the potential therapeutic effects and side effects of new compounds, ultimately leading to the development of safer and more effective medications.
Used in Drug Synthesis Optimization:
As a protective group, the benzyloxycarbonyl group (Bzl or Z) in Z-HIS(BZL)-OH is used to increase the effectiveness and optimization of synthesized drugs. This helps in improving the overall yield and quality of the final drug product, ensuring that the medication is both potent and stable.
Used in Chemical Research:
Z-HIS(BZL)-OH is used as a chemical compound in various research studies, providing insights into the properties and reactivity of amino acids and peptides. This information is crucial for the advancement of our understanding of biological processes and the development of new chemical methodologies.
Check Digit Verification of cas no
The CAS Registry Mumber 21929-66-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,2 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.Calculate Digit Verification of CAS Registry Number 21929-66:
(7*2)+(6*1)+(5*9)+(4*2)+(3*9)+(2*6)+(1*6)=118
118 % 10 = 8
So 21929-66-8 is a valid CAS Registry Number.
InChI:InChI=1/C21H21N3O4/c25-20(26)19(23-21(27)28-14-17-9-5-2-6-10-17)11-18-13-24(15-22-18)12-16-7-3-1-4-8-16/h1-10,13,15,19H,11-12,14H2,(H,23,27)(H,25,26)
21929-66-8Upstream product
21929-66-8Downstream Products
- 120548-57-4 N-(1-benzyl-Nα-benzyloxycarbonyl-L-histidyl)-glycine-benzyl ester
- 108722-10-7 1-benzyl-Nα-benzyloxycarbonyl-L-histidyl=>L-valyl=>L-tyrosine-methyl ester
- 30891-94-2 benzyl-N-carboxy-L-histidine anhydride
- 95485-20-4 Nα-carbobenzoxy-Nim-benzyl-L-histidine methyl ester hydrochloride
- 66438-51-5 Nα-carbobenzoxy-Nim-benzyl-L-histidine pentachlorophenyl ester
- 95433-50-4 N-(carbobenzyloxy)-im-benzylhistidine cyanomethyl ester
- 122766-72-7 1-benzyl-Nα-(1-benzyl-Nα-benzyloxycarbonyl-L-histidyl)-L-histidine-benzyl ester
- 105374-43-4 N-(1-benzyl-Nα-benzyloxycarbonyl-L-histidyl)-glycine
- 1059596-74-5 N-Cbz-N'-benzyl-L-histidine p-tolylthiol ester
- 26582-89-8 Nα-carbobenzoxy-Nim-benzyl-L-histidine hydrazide
- 95485-23-7 Nα-carbobenzoxy-Nim-benzyl-L-histidyl-L-valine methyl ester
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Z-HIS(BZL)-OH
