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6-Fluorocytosine is a fluorinated cytosine derivative characterized by the presence of a fluorine atom at the 6th position of the cytosine molecule. It is primarily recognized for its antifungal properties, particularly in the treatment of infections caused by Candida species. 6-FLUOROCYTOSINE is metabolized by fungal cytosine deaminase into 5-fluorouracil, which then integrates into fungal RNA and DNA, causing metabolic disruption and cell death. While it has limited activity against bacteria, 6-Fluorocytosine also exhibits some potential for antitumor activity. However, its use requires careful consideration due to the risk of toxicity, especially to bone marrow and gastrointestinal cells.

2193-47-7

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2193-47-7 Usage

Uses

Used in Antifungal Applications:
6-Fluorocytosine is used as an antifungal agent for the treatment of specific fungal infections, particularly those caused by Candida species. It functions by being converted into 5-fluorouracil, which disrupts the fungal cell metabolism, leading to cell death and clearing the infection.
Used in Oncology Research:
6-Fluorocytosine is used as a potential antitumor agent in the field of oncology. Its mechanism of action in this context is under investigation, but it has shown some promise in inhibiting tumor growth, warranting further research into its potential applications in cancer treatment.
Used in Pharmaceutical Formulation:
6-Fluorocytosine is used as an active pharmaceutical ingredient in the formulation of medications designed to combat fungal infections. Its incorporation into drug products allows for targeted treatment of the specified infections while minimizing the impact on the patient's overall health, given its specificity for fungal cells.

Check Digit Verification of cas no

The CAS Registry Mumber 2193-47-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,9 and 3 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2193-47:
(6*2)+(5*1)+(4*9)+(3*3)+(2*4)+(1*7)=77
77 % 10 = 7
So 2193-47-7 is a valid CAS Registry Number.
InChI:InChI=1/C4H4FN3O/c5-2-1-3(6)8-4(9)7-2/h1H,(H3,6,7,8,9)

2193-47-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-amino-6-fluoro-1H-pyrimidin-2-one

1.2 Other means of identification

Product number -
Other names 4-Amino-6-fluoro-2(1H)-pyrimidinone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2193-47-7 SDS

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