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2193-87-5

2193-87-5

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  • (8S,9R,10S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-7,8,11,12,14,15-hexahydro-6H-cyclopenta[a]phenanthren-3-one

    Cas No: 2193-87-5

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2193-87-5 Usage

Uses

Fluprednidene is obtained from Fluprednidene Acetate (F598600) which is a Anti-inflammatory (topical).

Check Digit Verification of cas no

The CAS Registry Mumber 2193-87-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,9 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2193-87:
(6*2)+(5*1)+(4*9)+(3*3)+(2*8)+(1*7)=85
85 % 10 = 5
So 2193-87-5 is a valid CAS Registry Number.
InChI:InChI=1/C22H27FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,15-17,24,26,28H,1,4-5,8,10-11H2,2-3H3/t15-,16-,17?,19-,20-,21-,22-/m0/s1

2193-87-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-7,8,11,12,14,15-hexahydro-6H-cyclopenta[a]phenanthren-3-one

1.2 Other means of identification

Product number -
Other names Fluprednidene (INN)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2193-87-5 SDS

2193-87-5Upstream product

2193-87-5Downstream Products

2193-87-5Relevant articles and documents

Novel glucocorticoid antedrugs possessing a C16,17-fused γ-lactone ring

Biggadikc, Keith,Lynn, Scan M.,Procopiou, Panayiotis A.,Shaw,Williamson, Christopher

, p. 813 - 818 (2000)

A series of novel γ-butyrolactones fused at the 16β,17β position of the 9α-fluoro-1 1β-hydroxy-3-oxoandrosta-1,4-diene nucleus and possessing oxygen substituents at 16α, 17α positions were prepared and tested as glucocorticoid agonists. The compounds were also tested for their lability in human plasma. Lactone 5 was found to be rapidly hydrolysed in plasma, whereas derivative 18? was found to be a potent glucocorticoid agonist, but was stable in plasma. The structure of the C21S diastereoisomer of compound 18 was confirmed by an X-ray diffraction study. The Royal Society of Chemistry 2000.

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