2193-87-5 Usage
Uses
Used in Pharmaceutical Industry:
Fluprednidene is used as a topical anti-inflammatory agent for the treatment of various skin disorders, such as eczema, dermatitis, and psoriasis. Its anti-inflammatory and immunosuppressive effects help alleviate symptoms like redness, itching, and swelling, providing relief to patients suffering from these conditions.
Additionally, fluprednidene may be used in combination with other medications or therapies to enhance the overall effectiveness of treatment and improve patient outcomes. Its precise mechanism of action involves the modulation of immune responses and the reduction of inflammation at the site of application, making it a valuable asset in dermatological care.
Check Digit Verification of cas no
The CAS Registry Mumber 2193-87-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,9 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2193-87:
(6*2)+(5*1)+(4*9)+(3*3)+(2*8)+(1*7)=85
85 % 10 = 5
So 2193-87-5 is a valid CAS Registry Number.
InChI:InChI=1/C22H27FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,15-17,24,26,28H,1,4-5,8,10-11H2,2-3H3/t15-,16-,17?,19-,20-,21-,22-/m0/s1
2193-87-5Relevant academic research and scientific papers
Biggadikc, Keith,Lynn, Scan M.,Procopiou, Panayiotis A.,Shaw,Williamson, Christopher
, p. 813 - 818 (2000)
A series of novel γ-butyrolactones fused at the 16β,17β position of the 9α-fluoro-1 1β-hydroxy-3-oxoandrosta-1,4-diene nucleus and possessing oxygen substituents at 16α, 17α positions were prepared and tested as glucocorticoid agonists. The compounds were also tested for their lability in human plasma. Lactone 5 was found to be rapidly hydrolysed in plasma, whereas derivative 18? was found to be a potent glucocorticoid agonist, but was stable in plasma. The structure of the C21S diastereoisomer of compound 18 was confirmed by an X-ray diffraction study. The Royal Society of Chemistry 2000.
