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Uridine 5'-diphosphoric acid disodium salt, also known as Uridine-5'-diphosphate disodium salt, is a phosphorylated derivative of the nucleoside Uridine. It is an endogenous metabolite that plays a crucial role in the biosynthesis of nucleic acids, specifically RNA. URIDINE 5'-DIPHOSPHORIC ACID DISODIUM SALT is a potent and selective P2Y6 receptor native agonist, with an EC50 value of 300 nM for the human P2Y6 receptor. Uridine 5'-diphosphoric acid disodium salt also catalyzes the glucuronidation of a wide array of substrates, making it an essential component in various biological processes.

21931-53-3

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21931-53-3 Usage

Uses

Used in Pharmaceutical Industry:
Uridine 5'-diphosphoric acid disodium salt is used as a pharmaceutical intermediate for the synthesis of various nucleoside analogs and antiviral drugs. Its role in RNA biosynthesis and its ability to modulate the activity of the P2Y6 receptor make it a valuable compound in the development of new therapeutic agents.
Used in Research Applications:
In the field of research, Uridine 5'-diphosphoric acid disodium salt is used as a biochemical tool to study the function and regulation of the P2Y6 receptor. It helps researchers understand the role of this receptor in various physiological processes and its potential as a target for drug discovery.
Used in Diagnostic Applications:
Uridine 5'-diphosphoric acid disodium salt can be used in diagnostic assays to detect and measure the activity of enzymes involved in the glucuronidation process. This can help in the identification of genetic disorders and metabolic diseases related to the dysfunction of these enzymes.
Used in Nutraceutical Industry:
As a component of certain dietary supplements, Uridine 5'-diphosphoric acid disodium salt may be used to support cognitive function and brain health. Its role in RNA synthesis and its potential to modulate the P2Y6 receptor could contribute to the maintenance of healthy neuronal function.

Biochem/physiol Actions

P2Y receptor agonist.

in vitro

Uridine-5'-diphosphate disodium salt (100 μM; for 15 min) significantly induces microglial CCL2 and CCL3 mRNA expression.

Check Digit Verification of cas no

The CAS Registry Mumber 21931-53-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,3 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 21931-53:
(7*2)+(6*1)+(5*9)+(4*3)+(3*1)+(2*5)+(1*3)=93
93 % 10 = 3
So 21931-53-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H14N2O12P2.Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);

21931-53-3 Well-known Company Product Price

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  • Sigma

  • (U4125)  Uridine5′-(trihydrogendiphosphate)sodiumsaltfromSaccharomycescerevisiae  95-100%

  • 21931-53-3

  • U4125-25MG

  • 255.06CNY

  • Detail
  • Sigma

  • (U4125)  Uridine5′-(trihydrogendiphosphate)sodiumsaltfromSaccharomycescerevisiae  95-100%

  • 21931-53-3

  • U4125-100MG

  • 650.52CNY

  • Detail
  • Sigma

  • (U4125)  Uridine5′-(trihydrogendiphosphate)sodiumsaltfromSaccharomycescerevisiae  95-100%

  • 21931-53-3

  • U4125-500MG

  • 2,340.00CNY

  • Detail
  • Sigma

  • (U4125)  Uridine5′-(trihydrogendiphosphate)sodiumsaltfromSaccharomycescerevisiae  95-100%

  • 21931-53-3

  • U4125-1G

  • 3,908.97CNY

  • Detail

21931-53-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Uridine 5,-Diphosphate Sodium Salt

1.2 Other means of identification

Product number -
Other names Uridine 5'-diphosphate sodium salt

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:21931-53-3 SDS

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