219319-76-3Relevant academic research and scientific papers
On the reaction of (S)-trifluoroacetoxysuccinic anhydride with amines to produce hydroxysuccinamic (malamic) acid derivatives
Lorenz, Peter,Stermitz, Frank R.,Beck, John J.
experimental part, p. 733 - 737 (2011/10/12)
L-Malic acid (2) reacts with trifluoroacetic anhydride under anhydrous conditions to give (S)-trifluoroacetoxysuccinic acid anhydride (3). The anhydride 3 undergoes regioselective ring opening with an excess of anilines or primary aliphatic amines leading
